SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3nuf PRD-CONTAINING
TRANSCRIPTION
REGULATOR
(Lactobacillus
paracasei) 		5 / 12 VAL A  34
LEU A  37
LEU A  53
ALA A  89
LEU A 107
 None
 1.12A 2aylA-3nufA:
undetectable		 2aylA-3nufA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nuf PRD-CONTAINING
TRANSCRIPTION
REGULATOR
(Lactobacillus
paracasei) 		5 / 12 ALA A  39
ALA A  38
LEU A  88
ALA A  40
LEU A  53
 None
 1.01A 3h0aA-3nufA:
undetectable		 3h0aA-3nufA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 3nuf PRD-CONTAINING
TRANSCRIPTION
REGULATOR
(Lactobacillus
paracasei) 		5 / 12 LEU A 107
PHE A  45
TYR A  33
SER A  85
LEU A  88
 None
None
EDO  A 308 (-4.4A)
None
None
 1.33A 4ot2A-3nufA:
3.5		 4ot2A-3nufA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3nuf PRD-CONTAINING
TRANSCRIPTION
REGULATOR
(Lactobacillus
paracasei) 		5 / 12 ASP A  90
THR A   2
ALA A  40
ALA A  41
TYR A  33
 None
None
None
None
EDO  A 308 (-4.4A)
 1.48A 4u15B-3nufA:
undetectable		 4u15B-3nufA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 3nuf PRD-CONTAINING
TRANSCRIPTION
REGULATOR
(Lactobacillus
paracasei) 		5 / 12 LEU A 107
PHE A  45
TYR A  33
SER A  85
LEU A  88
 None
None
EDO  A 308 (-4.4A)
None
None
 1.34A 4zbrA-3nufA:
3.4		 4zbrA-3nufA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KT8_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3nuf PRD-CONTAINING
TRANSCRIPTION
REGULATOR
(Lactobacillus
paracasei) 		5 / 9 GLU A 103
VAL A  93
GLY A  62
SER A  64
LEU A  61
 None
None
EDO  A 307 (-3.4A)
None
EDO  A 307 ( 4.1A)
 1.12A 5kt8B-3nufA:
undetectable		 5kt8B-3nufA:
9.78