SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA502_1
(CYTOCHROME P450 2B6)		 3nul PROFILIN I
(Arabidopsis
thaliana) 		5 / 11 LEU A 101
GLU A  46
LEU A  65
PRO A  40
PHE A  39
 None
 1.25A 3ua5A-3nulA:
undetectable		 3ua5A-3nulA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3nul PROFILIN I
(Arabidopsis
thaliana) 		4 / 6 CYH A 115
LEU A  20
HIS A  10
LEU A  11
 None
 1.21A 5hpuC-3nulA:
undetectable
5hpuD-3nulA:
undetectable		 5hpuC-3nulA:
8.70
5hpuD-3nulA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3nul PROFILIN I
(Arabidopsis
thaliana) 		4 / 6 VAL A  15
CYH A 115
HIS A  19
LEU A  20
 None
 1.29A 5hrqH-3nulA:
undetectable
5hrqK-3nulA:
undetectable
5hrqL-3nulA:
undetectable		 5hrqH-3nulA:
19.09
5hrqK-3nulA:
8.70
5hrqL-3nulA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3nul PROFILIN I
(Arabidopsis
thaliana) 		5 / 12 PRO A  40
LEU A  42
PHE A  39
HIS A  19
GLY A 104
 None
 1.12A 5k7uA-3nulA:
undetectable		 5k7uA-3nulA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3nul PROFILIN I
(Arabidopsis
thaliana) 		5 / 12 PRO A  40
LEU A  42
PHE A  39
HIS A  19
GLY A 104
 None
 1.10A 5l6eA-3nulA:
undetectable		 5l6eA-3nulA:
18.06