SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		4 / 6 GLU A 256
ASP A 227
PHE A 169
ARG A 164
 None
 1.37A 2a3bB-3nurA:
4.9		 2a3bB-3nurA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		4 / 7 SER A 238
LEU A 191
ILE A 240
GLY A 229
 None
 1.02A 2v0mC-3nurA:
undetectable		 2v0mC-3nurA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 11 ILE A 161
ALA A 165
ILE A 178
SER A 238
ILE A 240
 None
 1.04A 2w9sA-3nurA:
undetectable		 2w9sA-3nurA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 11 ILE A 161
ALA A 165
ILE A 178
SER A 238
ILE A 240
 None
 1.07A 2w9sB-3nurA:
undetectable		 2w9sB-3nurA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 10 ILE A 161
ALA A 165
ILE A 178
SER A 238
ILE A 240
 None
 1.07A 2w9sC-3nurA:
undetectable		 2w9sC-3nurA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 12 LEU A 351
VAL A 130
ILE A 151
PHE A 147
PHE A 132
 None
 1.27A 2weyA-3nurA:
undetectable		 2weyA-3nurA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		4 / 8 LEU A 350
VAL A  91
TYR A 190
LEU A 312
 None
 0.89A 3v81C-3nurA:
undetectable		 3v81C-3nurA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 12 LEU A 135
ALA A 143
ALA A 182
ILE A 189
ALA A 159
 None
 0.97A 4o2bD-3nurA:
undetectable		 4o2bD-3nurA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		3 / 3 SER A 285
ASP A 173
ASP A 242
 None
 0.79A 4uckA-3nurA:
undetectable		 4uckA-3nurA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 12 PRO A 195
SER A  98
HIS A  30
GLY A  95
HIS A 192
 None
None
CA  A 358 (-3.5A)
None
CA  A 358 (-3.5A)
 1.41A 5eeiA-3nurA:
undetectable		 5eeiA-3nurA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 12 PRO A 195
SER A  98
HIS A  30
GLY A  95
HIS A 192
 None
None
CA  A 358 (-3.5A)
None
CA  A 358 (-3.5A)
 1.41A 5eeiB-3nurA:
undetectable		 5eeiB-3nurA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		4 / 7 HIS A 231
HIS A 192
ILE A 161
ARG A 164
 None
CA  A 358 (-3.5A)
None
None
 0.99A 5kkzC-3nurA:
undetectable
5kkzE-3nurA:
undetectable		 5kkzC-3nurA:
20.96
5kkzE-3nurA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		4 / 7 HIS A 192
ILE A 161
ARG A 164
HIS A 231
 CA  A 358 (-3.5A)
None
None
None
 0.96A 5kkzK-3nurA:
undetectable
5kkzQ-3nurA:
undetectable		 5kkzK-3nurA:
23.16
5kkzQ-3nurA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		4 / 7 HIS A 231
HIS A 192
ILE A 161
ARG A 164
 None
CA  A 358 (-3.5A)
None
None
 0.99A 5kkzM-3nurA:
undetectable
5kkzO-3nurA:
undetectable		 5kkzM-3nurA:
20.96
5kkzO-3nurA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		5 / 12 LEU A 135
ALA A 143
ALA A 182
ILE A 189
ALA A 159
 None
 0.90A 5xiwB-3nurA:
undetectable		 5xiwB-3nurA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3nur AMIDOHYDROLASE
(Staphylococcus
aureus) 		3 / 3 SER A  98
SER A 100
ALA A 159
 None
 0.71A 6dwnC-3nurA:
undetectable		 6dwnC-3nurA:
13.84