SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nut'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		4 / 8 GLY A  13
GLY A  11
GLY A  81
LEU A  10
 GOL  A 248 (-3.7A)
None
SAH  A1501 (-3.5A)
GOL  A 248 (-4.0A)
 0.54A 1qzzA-3nutA:
3.7		 1qzzA-3nutA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		4 / 6 ARG A 189
THR A 239
ALA A 229
PRO A 126
 None
 1.36A 2ql8A-3nutA:
undetectable
2ql8B-3nutA:
undetectable		 2ql8A-3nutA:
21.01
2ql8B-3nutA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_1
(PROTEASE)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		5 / 9 ALA A 212
ASP A 211
ILE A 180
VAL A 225
ILE A 191
 None
 1.12A 3nuoA-3nutA:
undetectable		 3nuoA-3nutA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		5 / 12 TYR A 163
GLY A  11
SER A  80
LEU A  17
ALA A 120
 SAH  A1501 (-4.4A)
None
SAH  A1501 (-3.9A)
None
None
 1.32A 3ou7C-3nutA:
undetectable		 3ou7C-3nutA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		5 / 12 GLY A  81
LEU A  10
ASP A  16
VAL A  22
THR A  23
 SAH  A1501 (-3.5A)
GOL  A 248 (-4.0A)
None
None
None
 1.10A 4wnwA-3nutA:
undetectable		 4wnwA-3nutA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		4 / 7 VAL A 197
ILE A 204
VAL A 222
ALA A 194
 SAH  A1501 (-3.9A)
None
SAH  A1501 ( 4.2A)
None
 0.68A 5ospA-3nutA:
undetectable		 5ospA-3nutA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		4 / 7 VAL A 197
ILE A 204
VAL A 222
ALA A 194
 SAH  A1501 (-3.9A)
None
SAH  A1501 ( 4.2A)
None
 0.68A 5osrA-3nutA:
undetectable		 5osrA-3nutA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		5 / 11 GLY A  84
ASP A  82
ALA A  87
ALA A  89
ILE A 109
 None
None
SAH  A1501 (-3.5A)
None
GOL  A 246 (-4.5A)
 0.92A 5yk2A-3nutA:
undetectable		 5yk2A-3nutA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 3nut PRECORRIN-3
METHYLASE
(Rhodobacter
capsulatus) 		3 / 3 SER A 169
LYS A 168
SER A 167
 None
 0.82A 6az3P-3nutA:
undetectable		 6az3P-3nutA:
15.42