SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		5 / 11 GLY A 140
ILE A 154
SER A 155
VAL A 132
ILE A 127
 None
 1.06A 2nnhA-3nv7A:
undetectable		 2nnhA-3nv7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		4 / 5 TYR A   7
VAL A  87
SER A  25
GLY A  89
 None
 1.28A 3v4tA-3nv7A:
undetectable
3v4tD-3nv7A:
undetectable		 3v4tA-3nv7A:
18.05
3v4tD-3nv7A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		3 / 3 GLU A 114
TYR A  98
GLU A  99
 None
 0.83A 4ryaA-3nv7A:
undetectable		 4ryaA-3nv7A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		4 / 7 ASP A  20
ARG A  24
THR A 115
GLU A 114
 None
 0.95A 5btfA-3nv7A:
undetectable
5btfC-3nv7A:
undetectable
5btfD-3nv7A:
2.3		 5btfA-3nv7A:
15.18
5btfC-3nv7A:
15.18
5btfD-3nv7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		5 / 12 ILE A 135
GLY A 140
ALA A 142
TYR A 151
VAL A 146
 None
 1.03A 5hw4A-3nv7A:
undetectable		 5hw4A-3nv7A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		5 / 11 ILE A 135
GLY A 140
ALA A 142
TYR A 151
VAL A 146
 None
 1.09A 5hw4B-3nv7A:
undetectable		 5hw4B-3nv7A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		5 / 12 ILE A 135
GLY A 140
ALA A 142
TYR A 151
VAL A 146
 None
 1.07A 5hw4C-3nv7A:
undetectable		 5hw4C-3nv7A:
25.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		5 / 7 GLY A   9
THR A  10
PHE A  11
HIS A  18
ARG A  91
 ACY  A 162 (-3.6A)
SO4  A 160 (-4.0A)
ACY  A 162 (-4.1A)
SO4  A 158 ( 4.1A)
SO4  A 158 ( 3.8A)
 0.98A 6jnhA-3nv7A:
12.1		 6jnhA-3nv7A:
42.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Helicobacter
pylori) 		4 / 6 GLY A   9
THR A  10
HIS A  18
ARG A  91
 ACY  A 162 (-3.6A)
SO4  A 160 (-4.0A)
SO4  A 158 ( 4.1A)
SO4  A 158 ( 3.8A)
 1.10A 6jogA-3nv7A:
12.0		 6jogA-3nv7A:
42.86