SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		4 / 7 PHE A 346
ALA A 321
PHE A 123
PHE A 121
 None
 0.88A 1lqtA-3nvtA:
undetectable		 1lqtA-3nvtA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		4 / 7 PHE A 346
ALA A 321
PHE A 123
PHE A 121
 None
 0.87A 1lquA-3nvtA:
undetectable		 1lquA-3nvtA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		5 / 10 ILE A 248
ALA A 245
ALA A 244
ASN A 211
ILE A 195
 None
 1.04A 2aclC-3nvtA:
undetectable		 2aclC-3nvtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		5 / 10 ILE A 248
ALA A 245
ALA A 244
ASN A 214
ILE A 195
 None
 1.13A 2aclC-3nvtA:
undetectable		 2aclC-3nvtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		5 / 11 ILE A 248
ALA A 245
ALA A 244
ASN A 211
ILE A 195
 None
 1.11A 2aclE-3nvtA:
undetectable		 2aclE-3nvtA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		5 / 10 ALA A 209
LEU A 218
ALA A 244
SER A 235
LEU A 234
 None
 1.25A 2bxeA-3nvtA:
3.3		 2bxeA-3nvtA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		4 / 6 LEU A 112
LEU A 148
PRO A 227
VAL A 204
 None
 1.08A 2dqyC-3nvtA:
undetectable		 2dqyC-3nvtA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		4 / 8 PRO A 306
ALA A 308
ALA A 311
THR A 298
 None
 0.83A 3dtuC-3nvtA:
undetectable
3dtuD-3nvtA:
undetectable		 3dtuC-3nvtA:
21.91
3dtuD-3nvtA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		4 / 7 LYS A 231
ARG A 157
VAL A 185
ILE A 149
 ACT  A 363 (-2.3A)
None
None
None
 0.63A 3gp0A-3nvtA:
undetectable		 3gp0A-3nvtA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		4 / 7 VAL A 329
PRO A 325
ILE A 340
SER A 130
 None
 0.99A 5vkqA-3nvtA:
undetectable
5vkqD-3nvtA:
undetectable		 5vkqA-3nvtA:
14.00
5vkqD-3nvtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		4 / 9 TYR A 201
ILE A 228
ILE A 256
LEU A 258
 None
 0.83A 5vkqB-3nvtA:
undetectable
5vkqC-3nvtA:
undetectable		 5vkqB-3nvtA:
14.00
5vkqC-3nvtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		5 / 12 VAL A 204
MET A 291
VAL A 294
PHE A 346
GLY A 124
 None
 1.41A 6brdA-3nvtA:
undetectable		 6brdA-3nvtA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE
(Listeria
monocytogenes) 		5 / 10 GLY A 170
GLN A 133
VAL A 134
GLU A 169
PHE A 154
 None
 1.10A 6nqaK-3nvtA:
undetectable		 6nqaK-3nvtA:
20.93