SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nvx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3nvx PROTEIN A39
(Vaccinia
virus) 		3 / 3 ALA A 384
VAL A 374
TRP A 329
 None
 0.96A 1c4dA-3nvxA:
undetectable
1c4dB-3nvxA:
undetectable		 1c4dA-3nvxA:
3.69
1c4dB-3nvxA:
3.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 ALA A 159
ALA A 103
PRO A 104
LEU A 120
VAL A 119
 None
 1.07A 2zifB-3nvxA:
undetectable		 2zifB-3nvxA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3nvx PROTEIN A39
(Vaccinia
virus) 		4 / 5 ILE A 352
THR A 362
PHE A 321
PHE A 245
 None
 1.38A 3em0A-3nvxA:
2.0		 3em0A-3nvxA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 3nvx PROTEIN A39
(Vaccinia
virus) 		4 / 7 PHE A 245
PHE A 346
SER A 253
TYR A 225
 None
 1.41A 3hggA-3nvxA:
undetectable		 3hggA-3nvxA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3nvx PROTEIN A39
(Vaccinia
virus) 		3 / 3 ASN A  59
ASN A 107
GLU A  23
 None
 0.92A 3kpdC-3nvxA:
undetectable		 3kpdC-3nvxA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3nvx PROTEIN A39
(Vaccinia
virus) 		3 / 3 ASN A  59
ASN A 107
GLU A  23
 None
 0.92A 3kpdB-3nvxA:
undetectable		 3kpdB-3nvxA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 ILE A 112
LEU A  30
ILE A 388
THR A  27
ILE A 383
 None
 1.03A 3pwwA-3nvxA:
undetectable		 3pwwA-3nvxA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		4 / 5 THR A 262
THR A 233
HIS A 230
LEU A 173
 None
 1.31A 5axaC-3nvxA:
undetectable		 5axaC-3nvxA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.87A 5ec8C-3nvxA:
undetectable		 5ec8C-3nvxA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.93A 5ehiA-3nvxA:
undetectable		 5ehiA-3nvxA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.93A 5eiwA-3nvxA:
undetectable		 5eiwA-3nvxA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.95A 5ekxA-3nvxA:
undetectable		 5ekxA-3nvxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.96A 5kqrA-3nvxA:
undetectable		 5kqrA-3nvxA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.91A 5wz1B-3nvxA:
undetectable		 5wz1B-3nvxA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.90A 5wz2A-3nvxA:
undetectable		 5wz2A-3nvxA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3nvx PROTEIN A39
(Vaccinia
virus) 		5 / 12 GLY A 101
GLY A  99
GLY A  78
ASP A 143
ILE A 125
 None
 0.86A 5wz2B-3nvxA:
undetectable		 5wz2B-3nvxA:
21.59