SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nwa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
3 / 3 ASN B 108
ALA B 111
ASN B 621
None
0.82A 1n4fA-3nwaB:
undetectable
1n4fA-3nwaB:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 12 ALA B 390
SER B 388
ARG B 377
TYR B 429
TYR B 452
None
1.23A 1xvaB-3nwaB:
undetectable
1xvaB-3nwaB:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.96A 2f16K-3nwaB:
undetectable
2f16L-3nwaB:
undetectable
2f16K-3nwaB:
13.95
2f16L-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.94A 2f16Y-3nwaB:
undetectable
2f16Z-3nwaB:
undetectable
2f16Y-3nwaB:
13.95
2f16Z-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
4 / 7 LEU B 449
GLY B 414
ARG B 418
PHE B 150
None
0.89A 2wq5A-3nwaB:
undetectable
2wq5A-3nwaB:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
3 / 3 LEU B 330
VAL B 276
ARG B 245
None
0.70A 3b0wB-3nwaB:
undetectable
3b0wB-3nwaB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 3mg0K-3nwaB:
undetectable
3mg0L-3nwaB:
undetectable
3mg0K-3nwaB:
13.95
3mg0L-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
3 / 3 TYR B 213
ASP B 167
ASP B 188
None
0.81A 3r24A-3nwaB:
undetectable
3r24A-3nwaB:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
3 / 3 TYR B 301
GLU B 286
TYR B 296
None
0.97A 3ug8A-3nwaB:
undetectable
3ug8A-3nwaB:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 THR B 394
ALA B 504
PHE B 503
SER B 387
ILE B 450
None
1.38A 4claA-3nwaB:
undetectable
4claA-3nwaB:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
4 / 8 ASN B 112
THR B 642
LEU B 617
LEU B 623
None
0.77A 4ejgB-3nwaB:
undetectable
4ejgB-3nwaB:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
4 / 8 PHE B 508
ILE B 391
SER B 387
ALA B 147
None
1.02A 4eyzA-3nwaB:
undetectable
4eyzA-3nwaB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
4 / 8 PHE B 508
ILE B 391
SER B 387
ALA B 147
None
1.01A 4eyzB-3nwaB:
undetectable
4eyzB-3nwaB:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
3 / 3 TYR B 213
PHE B 186
ARG B 215
None
1.14A 4g19D-3nwaB:
undetectable
4g19D-3nwaB:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 4qvlK-3nwaB:
undetectable
4qvlL-3nwaB:
undetectable
4qvlK-3nwaB:
13.95
4qvlL-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 4qvlY-3nwaB:
undetectable
4qvlZ-3nwaB:
undetectable
4qvlY-3nwaB:
13.95
4qvlZ-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 9 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.96A 4qvmK-3nwaB:
undetectable
4qvmL-3nwaB:
undetectable
4qvmK-3nwaB:
13.95
4qvmL-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.96A 4qvmY-3nwaB:
undetectable
4qvmZ-3nwaB:
undetectable
4qvmY-3nwaB:
13.95
4qvmZ-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 9 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.96A 4qvnK-3nwaB:
undetectable
4qvnL-3nwaB:
undetectable
4qvnK-3nwaB:
13.95
4qvnL-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 9 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 4qvnY-3nwaB:
undetectable
4qvnZ-3nwaB:
undetectable
4qvnY-3nwaB:
13.95
4qvnZ-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.96A 4qvpK-3nwaB:
undetectable
4qvpL-3nwaB:
undetectable
4qvpK-3nwaB:
14.10
4qvpL-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.96A 4qvpY-3nwaB:
undetectable
4qvpZ-3nwaB:
undetectable
4qvpY-3nwaB:
14.10
4qvpZ-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 9 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.94A 4qvqK-3nwaB:
undetectable
4qvqL-3nwaB:
undetectable
4qvqK-3nwaB:
13.95
4qvqL-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 9 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.94A 4qvqY-3nwaB:
undetectable
4qvqZ-3nwaB:
undetectable
4qvqY-3nwaB:
13.95
4qvqZ-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.97A 4qw1K-3nwaB:
undetectable
4qw1L-3nwaB:
undetectable
4qw1K-3nwaB:
13.95
4qw1L-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.97A 4qw1Y-3nwaB:
undetectable
4qw1Z-3nwaB:
undetectable
4qw1Y-3nwaB:
13.95
4qw1Z-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 4qw3K-3nwaB:
undetectable
4qw3L-3nwaB:
undetectable
4qw3K-3nwaB:
13.95
4qw3L-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 10 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 4qw3Y-3nwaB:
undetectable
4qw3Z-3nwaB:
undetectable
4qw3Y-3nwaB:
13.95
4qw3Z-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
4 / 5 LEU B 330
ASP B 329
TYR B 164
THR B 162
None
1.28A 4wozF-3nwaB:
undetectable
4wozH-3nwaB:
undetectable
4wozF-3nwaB:
17.95
4wozH-3nwaB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 5bxnK-3nwaB:
undetectable
5bxnL-3nwaB:
undetectable
5bxnK-3nwaB:
13.95
5bxnL-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 5bxnY-3nwaB:
undetectable
5bxnZ-3nwaB:
undetectable
5bxnY-3nwaB:
13.95
5bxnZ-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 9 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.95A 5d0xK-3nwaB:
undetectable
5d0xL-3nwaB:
undetectable
5d0xK-3nwaB:
13.92
5d0xL-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 9 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.94A 5d0xY-3nwaB:
undetectable
5d0xZ-3nwaB:
undetectable
5d0xY-3nwaB:
13.92
5d0xZ-3nwaB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
4 / 7 TYR B 164
THR B 351
THR B 346
LEU B 234
None
1.09A 5jq7B-3nwaB:
0.6
5jq7B-3nwaB:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.91A 6hwdK-3nwaB:
undetectable
6hwdL-3nwaB:
undetectable
6hwdK-3nwaB:
10.17
6hwdL-3nwaB:
7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1)
5 / 11 ALA B 211
THR B 221
ALA B 222
ALA B 190
ASP B 188
None
0.91A 6hwdY-3nwaB:
undetectable
6hwdZ-3nwaB:
undetectable
6hwdY-3nwaB:
10.17
6hwdZ-3nwaB:
7.75