SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nwg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 9 LEU A  30
VAL A  52
ILE A  72
ILE A 104
ILE A  45
 None
 0.98A 1ohrB-3nwgA:
undetectable		 1ohrB-3nwgA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		4 / 7 LEU A  44
LEU A  31
SER A  85
VAL A 137
 None
 1.00A 1tyrB-3nwgA:
undetectable		 1tyrB-3nwgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		3 / 3 ASP A 112
THR A  88
PRO A  89
 None
 0.51A 2pynB-3nwgA:
undetectable		 2pynB-3nwgA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		3 / 3 ASP A 112
THR A  88
PRO A  89
 None
 0.56A 2q64B-3nwgA:
undetectable		 2q64B-3nwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		3 / 3 ASP A 112
THR A  88
PRO A  89
 None
 0.50A 2qakB-3nwgA:
undetectable		 2qakB-3nwgA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		3 / 3 MET A 162
GLU A   8
ASN A  10
 None
 1.10A 3a27A-3nwgA:
undetectable		 3a27A-3nwgA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A  30
VAL A  52
ILE A  72
ILE A 104
ILE A  45
 None
 0.85A 3bvbA-3nwgA:
undetectable		 3bvbA-3nwgA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 11 GLY A 153
ALA A 114
GLY A  97
ILE A  98
ILE A 125
 None
 1.04A 3ebzB-3nwgA:
undetectable		 3ebzB-3nwgA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 9 LEU A  30
VAL A  52
ILE A  72
ILE A 104
ILE A  45
 None
 1.03A 3el0B-3nwgA:
undetectable		 3el0B-3nwgA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A   6
LEU A  44
GLU A   8
ALA A  18
SER A 103
 None
 1.39A 4aqlA-3nwgA:
undetectable		 4aqlA-3nwgA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A  30
VAL A  52
ILE A  72
ILE A 104
ILE A  45
 None
 0.93A 4dqfA-3nwgA:
undetectable		 4dqfA-3nwgA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 11 LEU A  30
VAL A  52
ILE A  72
ILE A 104
ILE A  45
 None
 0.96A 4njtA-3nwgA:
undetectable		 4njtA-3nwgA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 11 LEU A  30
VAL A  52
ILE A  72
ILE A 104
ILE A  45
 None
 0.89A 4njtC-3nwgA:
undetectable		 4njtC-3nwgA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		3 / 3 ASP A  69
LEU A   6
PHE A  71
 None
 0.74A 4pthA-3nwgA:
undetectable		 4pthA-3nwgA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 11 LEU A  30
VAL A  52
ILE A  72
ILE A 104
ILE A  45
 None
 0.98A 4qgiB-3nwgA:
undetectable		 4qgiB-3nwgA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		4 / 4 ALA A 151
VAL A 146
GLY A 118
THR A 117
 None
 1.13A 4ubeA-3nwgA:
undetectable		 4ubeA-3nwgA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3nwg MICROCOMPARTMENTS
PROTEIN
(Desulfitobacteri
um
hafniense) 		5 / 12 LEU A 122
ALA A 115
ILE A  84
ALA A  83
ILE A   4
 None
 1.25A 5eypB-3nwgA:
undetectable		 5eypB-3nwgA:
18.34