SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nwi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3nwi ZINC TRANSPORT
PROTEIN ZNTB
(Salmonella
enterica) 		3 / 3 MET A   3
CYH A 145
PRO A 219
 None
 1.27A 3h52C-3nwiA:
undetectable		 3h52C-3nwiA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3nwi ZINC TRANSPORT
PROTEIN ZNTB
(Salmonella
enterica) 		5 / 12 VAL A  17
SER A 120
TRP A  44
CYH A  43
VAL A 133
 None
 1.43A 3vt3A-3nwiA:
undetectable		 3vt3A-3nwiA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3nwi ZINC TRANSPORT
PROTEIN ZNTB
(Salmonella
enterica) 		5 / 12 MET A 109
VAL A 132
LEU A 136
LEU A 129
LEU A 149
 None
 0.85A 4m11B-3nwiA:
undetectable		 4m11B-3nwiA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3nwi ZINC TRANSPORT
PROTEIN ZNTB
(Salmonella
enterica) 		4 / 6 VAL A 126
LEU A 129
CYH A  94
LEU A 156
 None
None
ZN  A 265 (-2.5A)
None
 1.21A 5hrqB-3nwiA:
undetectable
5hrqI-3nwiA:
undetectable
5hrqJ-3nwiA:
undetectable		 5hrqB-3nwiA:
8.03
5hrqI-3nwiA:
7.66
5hrqJ-3nwiA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3nwi ZINC TRANSPORT
PROTEIN ZNTB
(Salmonella
enterica) 		3 / 3 VAL A  13
SER A  54
TRP A  57
 None
 1.08A 5jwaA-3nwiA:
undetectable		 5jwaA-3nwiA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 3nwi ZINC TRANSPORT
PROTEIN ZNTB
(Salmonella
enterica) 		5 / 12 GLY A   8
ILE A   6
LEU A  31
CYH A  43
LEU A  21
 None
 1.02A 6bq4A-3nwiA:
undetectable		 6bq4A-3nwiA:
16.41