SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nwj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 3nwj ATSK2
(Arabidopsis
thaliana) 		5 / 12 LEU A 256
GLY A 108
GLY A 110
LEU A 103
GLY A 115
 None
 1.21A 1y4lA-3nwjA:
undetectable		 1y4lA-3nwjA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3nwj ATSK2
(Arabidopsis
thaliana) 		3 / 3 ARG A 208
THR A 260
VAL A 268
 None
 0.89A 2qakA-3nwjA:
undetectable		 2qakA-3nwjA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3nwj ATSK2
(Arabidopsis
thaliana) 		3 / 3 TRP A 240
VAL A 268
ARG A 266
 None
 0.91A 3b0wA-3nwjA:
undetectable		 3b0wA-3nwjA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3nwj ATSK2
(Arabidopsis
thaliana) 		4 / 8 PRO A 273
ALA A 277
ALA A 280
ILE A 117
 None
 0.76A 3dtuC-3nwjA:
undetectable
3dtuD-3nwjA:
undetectable		 3dtuC-3nwjA:
19.89
3dtuD-3nwjA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3nwj ATSK2
(Arabidopsis
thaliana) 		5 / 12 PHE A 146
GLY A 150
ASP A 130
GLY A 177
ARG A 243
 None
 1.37A 3jzjA-3nwjA:
undetectable		 3jzjA-3nwjA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3nwj ATSK2
(Arabidopsis
thaliana) 		4 / 8 ILE A 278
ILE A 276
LEU A 271
ILE A 259
 None
 0.94A 4dtaB-3nwjA:
undetectable		 4dtaB-3nwjA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3nwj ATSK2
(Arabidopsis
thaliana) 		4 / 8 ALA A 250
GLY A 105
THR A 176
VAL A 174
 None
 0.85A 4r20A-3nwjA:
undetectable		 4r20A-3nwjA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 3nwj ATSK2
(Arabidopsis
thaliana) 		4 / 5 HIS A 191
ALA A 250
SER A 195
TYR A 287
 None
 1.34A 5yodF-3nwjA:
undetectable		 5yodF-3nwjA:
22.52