SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nwm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3nwm PEPTIDE/BETA-2MICROG
LOBULIN/MHC CLASS I
H-2KD CHIMERIC
PROTEIN
(Mus
musculus) 		4 / 4 THR A 178
LEU A 179
VAL A  28
LEU A   5
 None
 1.06A 1fbmB-3nwmA:
undetectable		 1fbmB-3nwmA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 3nwm PEPTIDE/BETA-2MICROG
LOBULIN/MHC CLASS I
H-2KD CHIMERIC
PROTEIN
(Mus
musculus) 		5 / 12 ILE A 213
ASP A 212
THR A 214
VAL A 261
PRO A 185
 None
 1.21A 2yzqA-3nwmA:
undetectable		 2yzqA-3nwmA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3nwm PEPTIDE/BETA-2MICROG
LOBULIN/MHC CLASS I
H-2KD CHIMERIC
PROTEIN
(Mus
musculus) 		5 / 12 TYR A  85
GLY A  10
GLY A  11
VAL A   7
TRP A 147
 None
 1.36A 3dlcA-3nwmA:
undetectable		 3dlcA-3nwmA:
19.72