SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nws'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.92A 1v55A-3nwsA:
undetectable
1v55J-3nwsA:
undetectable		 1v55A-3nwsA:
15.67
1v55J-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  53
PHE A  55
LEU A  92
PHE A  37
 None
 0.94A 1wrlE-3nwsA:
undetectable
1wrlF-3nwsA:
undetectable		 1wrlE-3nwsA:
20.00
1wrlF-3nwsA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.85A 2dyrN-3nwsA:
undetectable
2dyrW-3nwsA:
undetectable		 2dyrN-3nwsA:
15.67
2dyrW-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.90A 2eijN-3nwsA:
undetectable
2eijW-3nwsA:
undetectable		 2eijN-3nwsA:
15.67
2eijW-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.86A 2eikN-3nwsA:
undetectable
2eikW-3nwsA:
undetectable		 2eikN-3nwsA:
15.67
2eikW-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.88A 2eilN-3nwsA:
undetectable
2eilW-3nwsA:
undetectable		 2eilN-3nwsA:
15.67
2eilW-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.88A 2einN-3nwsA:
undetectable
2einW-3nwsA:
undetectable		 2einN-3nwsA:
15.67
2einW-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  53
SER A  81
PHE A  76
ASP A  78
 None
 1.16A 2vn1B-3nwsA:
undetectable		 2vn1B-3nwsA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.83A 3ablA-3nwsA:
undetectable
3ablJ-3nwsA:
undetectable		 3ablA-3nwsA:
15.67
3ablJ-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.76A 3ablN-3nwsA:
undetectable
3ablW-3nwsA:
undetectable		 3ablN-3nwsA:
15.67
3ablW-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.89A 3ag3A-3nwsA:
undetectable
3ag3J-3nwsA:
undetectable		 3ag3A-3nwsA:
15.67
3ag3J-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.82A 3ag3N-3nwsA:
undetectable
3ag3W-3nwsA:
undetectable		 3ag3N-3nwsA:
15.67
3ag3W-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		5 / 6 LEU A 115
SER A  43
ILE A  98
CYH A 124
PHE A 125
 None
 1.25A 3ko0B-3nwsA:
undetectable		 3ko0B-3nwsA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.88A 5iy5N-3nwsA:
undetectable
5iy5W-3nwsA:
undetectable		 5iy5N-3nwsA:
15.67
5iy5W-3nwsA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 0.93A 5xdxA-3nwsA:
undetectable
5xdxJ-3nwsA:
undetectable		 5xdxA-3nwsA:
15.67
5xdxJ-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 1.01A 5z86N-3nwsA:
undetectable
5z86W-3nwsA:
undetectable		 5z86N-3nwsA:
15.67
5z86W-3nwsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nws CELL DIVISION
CONTROL PROTEIN 13
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  89
ARG A 116
THR A  42
LEU A  41
 None
 1.01A 5zcoN-3nwsA:
undetectable
5zcoW-3nwsA:
undetectable		 5zcoN-3nwsA:
15.67
5zcoW-3nwsA:
14.98