SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3nwz BH2602 PROTEIN
(Bacillus
halodurans) 		4 / 5 VAL A 141
VAL A 142
PHE A 162
ARG A 100
 None
 1.39A 3bjwH-3nwzA:
undetectable		 3bjwH-3nwzA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3nwz BH2602 PROTEIN
(Bacillus
halodurans) 		5 / 12 MET A  97
VAL A 133
GLY A 159
VAL A 154
THR A 153
 None
 1.05A 3c6gB-3nwzA:
undetectable		 3c6gB-3nwzA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3nwz BH2602 PROTEIN
(Bacillus
halodurans) 		5 / 10 ASN A 114
HIS A 116
TYR A 117
GLY A 144
LYS A 145
 None
 1.44A 3pp7B-3nwzA:
undetectable		 3pp7B-3nwzA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3nwz BH2602 PROTEIN
(Bacillus
halodurans) 		4 / 8 ALA A  45
THR A  92
VAL A  66
SER A  56
 None
 0.76A 4r20A-3nwzA:
undetectable		 4r20A-3nwzA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 3nwz BH2602 PROTEIN
(Bacillus
halodurans) 		3 / 3 ARG A 127
GLU A 152
TYR A 125
 None
 0.94A 4r29D-3nwzA:
undetectable		 4r29D-3nwzA:
23.85