SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nx3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 4 HIS A 135
LEU A 205
LEU A 216
LEU A  93
 None
 1.18A 1a4lD-3nx3A:
undetectable		 1a4lD-3nx3A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 GLN A 263
ASN A 262
LEU A 215
SER A 269
 None
 1.16A 1hk2A-3nx3A:
2.2		 1hk2A-3nx3A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 GLN A 263
ASN A 262
LEU A 215
SER A 269
 None
 1.11A 1hk3A-3nx3A:
2.1		 1hk3A-3nx3A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 SER A 228
GLY A 229
LEU A 302
GLY A 224
PHE A 232
 None
 1.36A 1iolA-3nx3A:
3.3		 1iolA-3nx3A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 10 ASP A  40
GLY A  46
GLY A  44
ILE A 375
LEU A  50
 None
 1.12A 1x7pA-3nx3A:
2.3
1x7pB-3nx3A:
2.2		 1x7pA-3nx3A:
22.67
1x7pB-3nx3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 ALA A 109
THR A 245
PHE A 127
 None
 0.59A 2c6nB-3nx3A:
undetectable		 2c6nB-3nx3A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 PHE A 134
THR A 145
LEU A 157
ALA A 141
 None
 1.43A 2e1qD-3nx3A:
undetectable		 2e1qD-3nx3A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 ILE A 194
GLY A 333
THR A 309
GLY A 331
GLU A 313
 None
 1.35A 2fn1A-3nx3A:
undetectable		 2fn1A-3nx3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 ILE A 194
GLY A 333
THR A 309
GLY A 331
GLU A 313
 None
 1.31A 2fn1B-3nx3A:
undetectable		 2fn1B-3nx3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 VAL A  28
LEU A  39
MET A 384
PHE A  41
PHE A 334
 None
 1.50A 2jj8C-3nx3A:
undetectable		 2jj8C-3nx3A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 PHE A 293
PHE A 231
PHE A 232
 None
 0.76A 2od9A-3nx3A:
undetectable		 2od9A-3nx3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 LEU A 205
LEU A 208
ARG A 206
ILE A 183
ASP A 242
 None
 1.01A 2q6hA-3nx3A:
undetectable		 2q6hA-3nx3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 LEU A 205
LEU A 208
ARG A 206
ILE A 183
ASP A 242
 None
 1.02A 2q72A-3nx3A:
undetectable		 2q72A-3nx3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A 205
LEU A 208
ARG A 206
ILE A 183
ASP A 242
 None
 1.00A 2qb4A-3nx3A:
undetectable		 2qb4A-3nx3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 LEU A 205
LEU A 208
ARG A 206
ILE A 183
ASP A 242
 None
 1.02A 2qeiA-3nx3A:
undetectable		 2qeiA-3nx3A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 LEU A 205
LEU A 208
ARG A 206
ILE A 183
ASP A 242
 None
 1.07A 2qjuA-3nx3A:
undetectable		 2qjuA-3nx3A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 PHE A 293
PHE A 231
PHE A 232
 None
 0.76A 2qqgA-3nx3A:
undetectable		 2qqgA-3nx3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 10 ILE A 214
LEU A 215
GLY A 125
GLN A 126
THR A 180
 None
 1.14A 2wd9C-3nx3A:
4.4		 2wd9C-3nx3A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 4 ARG A 227
PHE A 231
LEU A 374
PHE A 334
 None
 1.48A 3ag3P-3nx3A:
0.0
3ag3W-3nx3A:
0.0		 3ag3P-3nx3A:
19.65
3ag3W-3nx3A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 9 ALA A 109
GLY A 140
ILE A 158
ALA A 129
ILE A 184
 None
 1.02A 3ektB-3nx3A:
undetectable		 3ektB-3nx3A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		6 / 12 GLY A 257
ALA A 258
ILE A 243
GLY A 108
THR A 278
VAL A  96
 None
 1.46A 3el4A-3nx3A:
undetectable		 3el4A-3nx3A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 LEU A 205
LEU A 208
ARG A 206
ILE A 183
ASP A 242
 None
 1.02A 3gwwA-3nx3A:
undetectable		 3gwwA-3nx3A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 PRO A 241
SER A  91
LEU A 185
SER A 187
 None
 1.41A 3ijxH-3nx3A:
undetectable		 3ijxH-3nx3A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 PRO A 241
SER A  91
LEU A 185
SER A 187
 None
 1.40A 3iluH-3nx3A:
undetectable		 3iluH-3nx3A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 TYR A 311
GLU A 386
LEU A 308
LYS A 307
 None
None
None
MG  A 397 ( 3.7A)
 1.28A 3k8mB-3nx3A:
undetectable		 3k8mB-3nx3A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 SER A 101
GLY A 102
THR A 103
 None
 0.19A 3k9wA-3nx3A:
undetectable		 3k9wA-3nx3A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 ALA A 197
GLU A 220
ALA A 233
MET A 335
 None
 1.38A 3r9tC-3nx3A:
undetectable		 3r9tC-3nx3A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 SER A 159
PHE A 127
LYS A 162
 None
 1.00A 3u88A-3nx3A:
undetectable		 3u88A-3nx3A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 VAL A 260
ALA A 258
VAL A 289
LEU A 250
PHE A 232
 None
 1.04A 3zosA-3nx3A:
undetectable
3zosB-3nx3A:
undetectable		 3zosA-3nx3A:
23.08
3zosB-3nx3A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 PHE A 232
THR A 278
LEU A 250
 None
 0.76A 4qztA-3nx3A:
undetectable		 4qztA-3nx3A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 GLY A  51
ILE A 381
SER A 385
ASP A  40
PRO A 372
 None
 1.21A 4rtrA-3nx3A:
3.7		 4rtrA-3nx3A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 3nx3 ACETYLORNITHINE
AMINOTRANSFERASE
(Campylobacter
jejuni) 		4 / 4 HIS A 236
VAL A 188
LEU A 332
ALA A 233
 None
 1.34A 6d8pB-3nx3A:
undetectable		 6d8pB-3nx3A:
19.25