SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3U5J_A_08HA1_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	4 / 7	TRP A 457 PRO A 458 ASN A 514 MET A 523	None None EDO A 1 (-3.3A) None	0.46A	3u5jA-3nxbA: 16.2	3u5jA-3nxbA: 32.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3U5K_A_08JA1_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	5 / 8	TRP A 457 PRO A 458 VAL A 463 ASN A 514 MET A 523	None None EDO A 1 (-4.3A) EDO A 1 (-3.3A) None	0.44A	3u5kA-3nxbA: 16.6	3u5kA-3nxbA: 32.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3U5K_B_08JB2_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	4 / 7	TRP A 457 PRO A 458 VAL A 463 ASN A 514	None None EDO A 1 (-4.3A) EDO A 1 (-3.3A)	0.41A	3u5kB-3nxbA: 16.6	3u5kB-3nxbA: 32.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3U5K_C_08JC3_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	5 / 8	TRP A 457 PRO A 458 VAL A 463 ASN A 514 MET A 523	None None EDO A 1 (-4.3A) EDO A 1 (-3.3A) None	0.49A	3u5kC-3nxbA: 16.6	3u5kC-3nxbA: 32.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3U5K_D_08JD4_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	5 / 8	TRP A 457 PRO A 458 VAL A 463 ASN A 514 MET A 523	None None EDO A 1 (-4.3A) EDO A 1 (-3.3A) None	0.50A	3u5kD-3nxbA: 16.6	3u5kD-3nxbA: 32.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4C66_A_H4CA1168_0 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	5 / 9	TRP A 457 PRO A 458 VAL A 463 ASN A 514 MET A 523	None None EDO A 1 (-4.3A) EDO A 1 (-3.3A) None	0.57A	4c66A-3nxbA: 16.3	4c66A-3nxbA: 32.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5PBE_A_TYLA2001_1 (BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	4 / 6	PRO A 458 VAL A 463 TYR A 471 ASN A 514	None EDO A 1 (-4.3A) None EDO A 1 (-3.3A)	0.46A	5pbeA-3nxbA: 17.3	5pbeA-3nxbA: 32.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5Y1Y_A_HNQA201_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	3nxb	CAT EYE SYNDROME CRITICAL REGION PROTEIN 2 (Homo sapiens)	5 / 8	PRO A 458 VAL A 463 CYH A 510 TYR A 513 ASN A 514	None EDO A 1 (-4.3A) EDO A 1 ( 3.9A) None EDO A 1 (-3.3A)	0.58A	5y1yA-3nxbA: 16.5	5y1yA-3nxbA: 32.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3U5J_A_08HA1_1","BROMODOMAIN-CONTAINING PROTEIN 4","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",4,"TRP A 457;PRO A 458;ASN A 514;MET A 523","None;None;EDO A   1 (-3.3A);None","0.46A","3u5jA-3nxbA:16.2","3u5jA-3nxbA:32.56"],["3U5K_A_08JA1_1","BROMODOMAIN-CONTAINING PROTEIN 4","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",5,"TRP A 457;PRO A 458;VAL A 463;ASN A 514;MET A 523","None;None;EDO A   1 (-4.3A);EDO A   1 (-3.3A);None","0.44A","3u5kA-3nxbA:16.6","3u5kA-3nxbA:32.56"],["3U5K_B_08JB2_1","BROMODOMAIN-CONTAINING PROTEIN 4","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",4,"TRP A 457;PRO A 458;VAL A 463;ASN A 514","None;None;EDO A   1 (-4.3A);EDO A   1 (-3.3A)","0.41A","3u5kB-3nxbA:16.6","3u5kB-3nxbA:32.56"],["3U5K_C_08JC3_1","BROMODOMAIN-CONTAINING PROTEIN 4","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",5,"TRP A 457;PRO A 458;VAL A 463;ASN A 514;MET A 523","None;None;EDO A   1 (-4.3A);EDO A   1 (-3.3A);None","0.49A","3u5kC-3nxbA:16.6","3u5kC-3nxbA:32.56"],["3U5K_D_08JD4_1","BROMODOMAIN-CONTAINING PROTEIN 4","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",5,"TRP A 457;PRO A 458;VAL A 463;ASN A 514;MET A 523","None;None;EDO A   1 (-4.3A);EDO A   1 (-3.3A);None","0.50A","3u5kD-3nxbA:16.6","3u5kD-3nxbA:32.56"],["4C66_A_H4CA1168_0","BROMODOMAIN-CONTAINING PROTEIN 4","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",5,"TRP A 457;PRO A 458;VAL A 463;ASN A 514;MET A 523","None;None;EDO A   1 (-4.3A);EDO A   1 (-3.3A);None","0.57A","4c66A-3nxbA:16.3","4c66A-3nxbA:32.56"],["5PBE_A_TYLA2001_1","BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",4,"PRO A 458;VAL A 463;TYR A 471;ASN A 514","None;EDO A   1 (-4.3A);None;EDO A   1 (-3.3A)","0.46A","5pbeA-3nxbA:17.3","5pbeA-3nxbA:32.77"],["5Y1Y_A_HNQA201_1","BROMODOMAIN-CONTAINING PROTEIN 4","3nxb","CAT EYE SYNDROME CRITICAL REGION PROTEIN 2","Homo sapiens",5,"PRO A 458;VAL A 463;CYH A 510;TYR A 513;ASN A 514","None;EDO A   1 (-4.3A);EDO A   1 ( 3.9A);None;EDO A   1 (-3.3A)","0.58A","5y1yA-3nxbA:16.5","5y1yA-3nxbA:32.50"]]