SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nxh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3nxh TRANSCRIPTIONAL
REGULATOR YVHJ
(Bacillus
subtilis) 		5 / 12 LEU A 239
ASN A 240
LEU A 242
LEU A 104
THR A 292
 None
 1.09A 1ya3C-3nxhA:
undetectable		 1ya3C-3nxhA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 3nxh TRANSCRIPTIONAL
REGULATOR YVHJ
(Bacillus
subtilis) 		4 / 7 TYR A 282
LEU A 104
ASP A 105
LYS A 109
 None
 1.42A 3lslA-3nxhA:
undetectable
3lslD-3nxhA:
undetectable		 3lslA-3nxhA:
24.58
3lslD-3nxhA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3nxh TRANSCRIPTIONAL
REGULATOR YVHJ
(Bacillus
subtilis) 		3 / 3 SER A 140
LEU A  80
MET A  82
 None
 0.85A 5ikrB-3nxhA:
undetectable		 5ikrB-3nxhA:
18.06