SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nyi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
0.96A 1ddsB-3nyiA:
undetectable
1ddsB-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 11 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.02A 1dhiB-3nyiA:
undetectable
1dhiB-3nyiA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
0.99A 1draB-3nyiA:
undetectable
1draB-3nyiA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.01A 1drbB-3nyiA:
undetectable
1drbB-3nyiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.05A 1dyiA-3nyiA:
undetectable
1dyiA-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.06A 1jolA-3nyiA:
undetectable
1jolA-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.06A 1jolB-3nyiA:
undetectable
1jolB-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_0
(NEURAMINIDASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 GLU A 244
ASP A 242
ILE A 282
GLU A 252
GLU A 248
None
1.46A 1l7hA-3nyiA:
undetectable
1l7hA-3nyiA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.02A 1rb2A-3nyiA:
undetectable
1rb2A-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
3 / 3 SER A  96
VAL A 272
LEU A  27
None
STE  A 301 ( 4.9A)
None
0.74A 1yajG-3nyiA:
undetectable
1yajG-3nyiA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
4 / 8 ASP A  21
LYS A   3
PHE A  87
ASP A   7
None
0.95A 2aouA-3nyiA:
undetectable
2aouA-3nyiA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 10 THR A 265
LEU A 130
VAL A 286
GLY A 285
VAL A 253
None
1.40A 2cp4A-3nyiA:
undetectable
2cp4A-3nyiA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.01A 2drcB-3nyiA:
undetectable
2drcB-3nyiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
4 / 7 VAL A 165
ARG A 210
GLY A 205
VAL A 180
None
0.93A 2y05A-3nyiA:
undetectable
2y05B-3nyiA:
undetectable
2y05A-3nyiA:
22.38
2y05B-3nyiA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.15A 2zzaA-3nyiA:
undetectable
2zzaA-3nyiA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 11 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.13A 2zzaB-3nyiA:
undetectable
2zzaB-3nyiA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.01A 3drcB-3nyiA:
undetectable
3drcB-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.01A 3ql0A-3nyiA:
undetectable
3ql0A-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 11 GLY A 199
ASP A 200
VAL A 180
ASN A 124
LEU A 171
None
None
None
STE  A 301 (-4.2A)
None
1.14A 3v8vB-3nyiA:
undetectable
3v8vB-3nyiA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 9 ILE A 269
GLY A 270
VAL A 165
THR A 277
GLY A 278
STE  A 301 (-4.5A)
None
None
STE  A 301 ( 4.7A)
None
1.31A 4acaB-3nyiA:
undetectable
4acaC-3nyiA:
undetectable
4acaB-3nyiA:
21.06
4acaC-3nyiA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.00A 4dfrB-3nyiA:
undetectable
4dfrB-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
3 / 3 PHE A 162
VAL A 267
ILE A 269
None
None
STE  A 301 (-4.5A)
0.64A 4emaA-3nyiA:
undetectable
4emaA-3nyiA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
0.99A 4fhbA-3nyiA:
undetectable
4fhbA-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.02A 4psyA-3nyiA:
undetectable
4psyA-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.03A 4pthA-3nyiA:
undetectable
4pthA-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.04A 4qleA-3nyiA:
undetectable
4qleA-3nyiA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
4 / 8 TYR A   2
PHE A 145
ASN A 115
ILE A 101
None
0.87A 4qoiA-3nyiA:
undetectable
4qoiB-3nyiA:
undetectable
4qoiA-3nyiA:
21.40
4qoiB-3nyiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
4 / 7 THR A 182
GLY A 186
ALA A 184
ILE A 206
None
0.94A 4txnA-3nyiA:
undetectable
4txnA-3nyiA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
4 / 7 THR A 182
GLY A 186
ALA A 184
ILE A 206
None
0.94A 4txnB-3nyiA:
undetectable
4txnB-3nyiA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
4 / 7 THR A 182
GLY A 186
ALA A 184
ILE A 206
None
0.94A 4txnC-3nyiA:
2.5
4txnC-3nyiA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
4 / 7 THR A 182
GLY A 186
ALA A 184
ILE A 206
None
0.95A 4txnD-3nyiA:
undetectable
4txnD-3nyiA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.05A 4x5gA-3nyiA:
undetectable
4x5gA-3nyiA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.03A 4x5hA-3nyiA:
undetectable
4x5hA-3nyiA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.01A 5e8qB-3nyiA:
undetectable
5e8qB-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.00A 5eajB-3nyiA:
undetectable
5eajB-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.03A 5hi6B-3nyiA:
undetectable
5hi6B-3nyiA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
3 / 3 LYS A   1
ASP A  21
ILE A 116
None
0.65A 5kc4E-3nyiA:
undetectable
5kc4E-3nyiA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 VAL A 272
LEU A  17
ALA A   9
THR A  23
PRO A  65
STE  A 301 ( 4.9A)
None
None
None
None
1.09A 5nd3B-3nyiA:
2.1
5nd3B-3nyiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ILE A 287
ALA A 129
ILE A 119
LEU A 152
THR A 265
None
1.00A 5ujxB-3nyiA:
undetectable
5ujxB-3nyiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 ALA A 274
VAL A 267
MET A 196
ALA A 129
LEU A  17
None
None
STE  A 301 ( 4.6A)
None
None
1.27A 5x23A-3nyiA:
undetectable
5x23A-3nyiA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 12 GLY A 270
ASN A 124
SER A   8
PHE A  93
THR A  62
None
STE  A 301 (-4.2A)
None
STE  A 301 (-4.1A)
STE  A 301 (-3.6A)
1.40A 5yf0A-3nyiA:
undetectable
5yf0A-3nyiA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 9 ASP A 262
ALA A 159
ILE A 287
SER A 236
GLY A 285
None
1.35A 6awoA-3nyiA:
undetectable
6awoA-3nyiA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)
3nyi FAT ACID-BINDING
PROTEIN

(Eubacterium
ventriosum)
5 / 9 ASP A 262
ALA A 159
ILE A 287
SER A 236
GLY A 285
None
1.35A 6awqA-3nyiA:
undetectable
6awqA-3nyiA:
22.30