SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RS7_A_ACTA860_0 (NITRIC-OXIDE SYNTHASE, BRAIN)	3nym	UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	4 / 5	GLY A 15 ILE A 12 TRP A 40 VAL A 27	None MLY A 8 ( 3.9A) MLY A 39 ( 4.1A) None	1.26A	1rs7A-3nymA: undetectable	1rs7A-3nymA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA5_A_STRA301_1 (MINERALOCORTICOID RECEPTOR)	3nym	UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	5 / 12	ASN A 76 LEU A 72 ALA A 71 SER A 83 LEU A 84	SO4 A 128 ( 3.5A) None PEG A 127 ( 4.2A) None None	1.30A	2aa5A-3nymA: undetectable	2aa5A-3nymA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA5_B_STRB302_1 (MINERALOCORTICOID RECEPTOR)	3nym	UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	5 / 12	ASN A 76 LEU A 72 ALA A 71 SER A 83 LEU A 84	SO4 A 128 ( 3.5A) None PEG A 127 ( 4.2A) None None	1.30A	2aa5B-3nymA: undetectable	2aa5B-3nymA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D33_A_ACTA860_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3nym	UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	4 / 5	GLY A 15 ILE A 12 TRP A 40 VAL A 27	None MLY A 8 ( 3.9A) MLY A 39 ( 4.1A) None	1.27A	4d33A-3nymA: undetectable	4d33A-3nymA: 13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D33_B_ACTB860_0 (NITRIC OXIDE SYNTHASE, ENDOTHELIAL)	3nym	UNCHARACTERIZED PROTEIN (Neisseria meningitidis)	4 / 5	GLY A 15 ILE A 12 TRP A 40 VAL A 27	None MLY A 8 ( 3.9A) MLY A 39 ( 4.1A) None	1.26A	4d33B-3nymA: undetectable	4d33B-3nymA: 13.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RS7_A_ACTA860_0","NITRIC-OXIDE SYNTHASE, BRAIN","3nym","UNCHARACTERIZED PROTEIN","Neisseria meningitidis",4,"GLY A  15;ILE A  12;TRP A  40;VAL A  27","None;MLY A   8 ( 3.9A);MLY A  39 ( 4.1A);None","1.26A","1rs7A-3nymA:undetectable","1rs7A-3nymA:16.43"],["2AA5_A_STRA301_1","MINERALOCORTICOID RECEPTOR","3nym","UNCHARACTERIZED PROTEIN","Neisseria meningitidis",5,"ASN A  76;LEU A  72;ALA A  71;SER A  83;LEU A  84","SO4 A 128 ( 3.5A);None;PEG A 127 ( 4.2A);None;None","1.30A","2aa5A-3nymA:undetectable","2aa5A-3nymA:18.75"],["2AA5_B_STRB302_1","MINERALOCORTICOID RECEPTOR","3nym","UNCHARACTERIZED PROTEIN","Neisseria meningitidis",5,"ASN A  76;LEU A  72;ALA A  71;SER A  83;LEU A  84","SO4 A 128 ( 3.5A);None;PEG A 127 ( 4.2A);None;None","1.30A","2aa5B-3nymA:undetectable","2aa5B-3nymA:18.75"],["4D33_A_ACTA860_0","NITRIC OXIDE SYNTHASE, ENDOTHELIAL","3nym","UNCHARACTERIZED PROTEIN","Neisseria meningitidis",4,"GLY A  15;ILE A  12;TRP A  40;VAL A  27","None;MLY A   8 ( 3.9A);MLY A  39 ( 4.1A);None","1.27A","4d33A-3nymA:undetectable","4d33A-3nymA:13.69"],["4D33_B_ACTB860_0","NITRIC OXIDE SYNTHASE, ENDOTHELIAL","3nym","UNCHARACTERIZED PROTEIN","Neisseria meningitidis",4,"GLY A  15;ILE A  12;TRP A  40;VAL A  27","None;MLY A   8 ( 3.9A);MLY A  39 ( 4.1A);None","1.26A","4d33B-3nymA:undetectable","4d33B-3nymA:13.69"]]