SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nyw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 9 TYR A  30
LEU A 220
VAL A  90
ILE A  10
ILE A  49
 None
 1.40A 1q6iA-3nywA:
undetectable		 1q6iA-3nywA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 11 ILE A  35
LEU A   7
LEU A  62
THR A 125
LEU A  89
 None
 1.19A 3a50C-3nywA:
undetectable		 3a50C-3nywA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  35
LEU A   7
LEU A  62
THR A 125
LEU A  89
 None
 1.21A 3a50E-3nywA:
undetectable		 3a50E-3nywA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ASN A 221
PRO A  59
GLY A  24
ILE A 216
LEU A  25
 None
 1.26A 3iv6A-3nywA:
6.7		 3iv6A-3nywA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  12
SER A  38
ASP A  65
ILE A  66
THR A  67
 None
 0.79A 3iv6A-3nywA:
6.7		 3iv6A-3nywA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 120
MET A 112
ILE A 117
SER A 169
 None
 1.22A 3pmzD-3nywA:
undetectable		 3pmzD-3nywA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 10 THR A  27
PRO A  59
ASN A  53
GLY A  29
ALA A  26
 None
 1.49A 3pp7B-3nywA:
undetectable		 3pp7B-3nywA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 163
LYS A 160
THR A 159
 None
 0.63A 4lj0A-3nywA:
undetectable		 4lj0A-3nywA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 11 ILE A  21
LEU A  34
LEU A  25
ALA A  26
VAL A 141
 None
 0.99A 5ji0A-3nywA:
undetectable		 5ji0A-3nywA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A   6
GLY A  18
ILE A  21
THR A  27
GLY A  29
 None
 0.85A 5koxA-3nywA:
3.8		 5koxA-3nywA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_A_SAMA501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  93
GLY A  18
GLY A 121
LEU A 166
LEU A 123
 None
 1.16A 5wwsA-3nywA:
7.6		 5wwsA-3nywA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3nyw PUTATIVE
OXIDOREDUCTASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 122
THR A  11
THR A 127
LEU A 166
 None
 1.06A 6f3mD-3nywA:
8.1		 6f3mD-3nywA:
20.38