SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nz8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR A 117
PRO A 147
THR A 116
PRO A 118
 None
 1.35A 1dsdC-3nz8A:
undetectable		 1dsdC-3nz8A:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 4 THR A 117
PRO A 147
THR A 116
PRO A 118
 None
 1.35A 1dsdC-3nz8A:
undetectable		 1dsdC-3nz8A:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.78A 1usqA-3nz8A:
undetectable		 1usqA-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.79A 1usqB-3nz8A:
undetectable		 1usqB-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.78A 1usqC-3nz8A:
undetectable		 1usqC-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.79A 1usqD-3nz8A:
undetectable		 1usqD-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.79A 1usqE-3nz8A:
undetectable		 1usqE-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.78A 1usqF-3nz8A:
undetectable		 1usqF-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.86A 2jkjA-3nz8A:
undetectable		 2jkjA-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.86A 2jkjB-3nz8A:
undetectable		 2jkjB-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.86A 2jkjC-3nz8A:
undetectable		 2jkjC-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.85A 2jkjE-3nz8A:
undetectable		 2jkjE-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.83A 2jklA-3nz8A:
undetectable		 2jklA-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.84A 2jklB-3nz8A:
undetectable		 2jklB-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.84A 2jklC-3nz8A:
undetectable		 2jklC-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.83A 2jklD-3nz8A:
undetectable		 2jklD-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.84A 2jklE-3nz8A:
1.4		 2jklE-3nz8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 GLY A  53
PRO A  52
ILE A  51
GLY A  55
 None
 0.84A 2jklF-3nz8A:
undetectable		 2jklF-3nz8A:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 ASN A  35
TRP A  50
GLY A  95
MET A 100
 None
 0.93A 2o5yH-3nz8A:
27.8
2o5yL-3nz8A:
15.6		 2o5yH-3nz8A:
60.27
2o5yL-3nz8A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL A  71
GLU A  10
LYS A  23
PHE A  29
 None
 1.34A 3rv5C-3nz8A:
undetectable
3rv5D-3nz8A:
undetectable		 3rv5C-3nz8A:
16.59
3rv5D-3nz8A:
16.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL A   2
TYR A  27
ARG A  94
TYR A 102
 None
 0.28A 4m7kH-3nz8A:
27.9		 4m7kH-3nz8A:
67.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA409_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL A  18
ILE A  20
VAL A 109
THR A 107
 None
 0.68A 4xdtA-3nz8A:
undetectable		 4xdtA-3nz8A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_A_FOLA201_0
(FOLATE ECF
TRANSPORTER)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		5 / 12 LEU A  69
SER A  56
PHE A  29
THR A  28
ASN A  35
 None
 1.25A 4z7fA-3nz8A:
undetectable		 4z7fA-3nz8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3nz8 MOUSE ANTI V3
ANTIBODY 7C8 FAB,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 ASN A  86
SER A  82
SER A  82
 None
 0.77A 5gsnA-3nz8A:
undetectable		 5gsnA-3nz8A:
21.76