SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		6 / 11 ALA A 223
THR A 256
ILE A 260
ASP A 245
LEU A 241
GLY A 248
 None
 1.45A 1b02A-3nzgA:
undetectable		 1b02A-3nzgA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		4 / 8 TYR A 212
PHE A 216
THR A 256
LEU A 226
 None
 1.31A 1ea1A-3nzgA:
undetectable		 1ea1A-3nzgA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 10 LEU A 361
ALA A 359
GLU A 358
ARG A 351
HIS A 139
 None
 1.33A 1gwrA-3nzgA:
undetectable		 1gwrA-3nzgA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		4 / 8 MET A 209
TYR A 337
ARG A 199
TYR A 235
 None
 1.46A 1xqlA-3nzgA:
8.2
1xqlB-3nzgA:
8.1		 1xqlA-3nzgA:
22.07
1xqlB-3nzgA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		4 / 8 TYR A 337
ARG A 199
TYR A 235
MET A 209
 None
 1.45A 1xqlA-3nzgA:
8.2
1xqlB-3nzgA:
8.0		 1xqlA-3nzgA:
22.07
1xqlB-3nzgA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 GLY A 293
LEU A  45
GLY A  46
GLY A 109
LEU A 354
 None
 0.91A 2zbpA-3nzgA:
undetectable		 2zbpA-3nzgA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 ILE A 320
GLY A 319
ALA A 359
VAL A 355
ASN A 379
 None
 1.10A 3jb3A-3nzgA:
undetectable		 3jb3A-3nzgA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 11 GLY A 262
THR A 240
LEU A 241
LEU A 246
LEU A 252
 None
 1.33A 3ndvA-3nzgA:
undetectable
3ndvB-3nzgA:
undetectable		 3ndvA-3nzgA:
23.73
3ndvB-3nzgA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 11 LEU A 252
GLY A 262
THR A 240
LEU A 241
LEU A 246
 None
 1.31A 3ndvA-3nzgA:
undetectable
3ndvB-3nzgA:
undetectable		 3ndvA-3nzgA:
23.73
3ndvB-3nzgA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 11 GLY A 262
THR A 240
LEU A 241
LEU A 246
LEU A 252
 None
 1.31A 3ndvC-3nzgA:
undetectable
3ndvD-3nzgA:
undetectable		 3ndvC-3nzgA:
23.73
3ndvD-3nzgA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 11 LEU A 252
GLY A 262
THR A 240
LEU A 241
LEU A 246
 None
 1.33A 3ndvC-3nzgA:
undetectable
3ndvD-3nzgA:
undetectable		 3ndvC-3nzgA:
23.73
3ndvD-3nzgA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 9 GLY A 109
ALA A  48
ASP A  49
GLY A 103
LEU A  56
 None
 1.05A 3u7sB-3nzgA:
undetectable		 3u7sB-3nzgA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 10 GLY A 103
ALA A 106
ILE A  71
LEU A  68
ILE A  61
 None
 1.03A 4dt8B-3nzgA:
undetectable		 4dt8B-3nzgA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 11 LEU A 294
ASP A 116
LEU A  45
GLY A  44
ALA A 323
 None
 1.26A 4fogD-3nzgA:
undetectable		 4fogD-3nzgA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 CYH A 291
GLY A 103
THR A 267
GLY A 293
LEU A 297
 None
 1.13A 4n48A-3nzgA:
undetectable		 4n48A-3nzgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 CYH A 291
GLY A 103
THR A 267
GLY A 293
LEU A 297
 None
 1.12A 4n48B-3nzgA:
undetectable		 4n48B-3nzgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 ALA A  54
SER A  51
GLY A  50
GLY A 103
PHE A 105
 None
 1.28A 4r29A-3nzgA:
undetectable		 4r29A-3nzgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 THR A 321
ILE A 110
GLY A 109
ASN A 289
VAL A  34
 None
 1.02A 4rvgA-3nzgA:
undetectable		 4rvgA-3nzgA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB402_0
(GLYCINE OXIDASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		4 / 5 MET A 104
GLU A 296
TYR A  91
ARG A 269
 None
 1.09A 4yshB-3nzgA:
undetectable		 4yshB-3nzgA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		4 / 7 ALA A 331
THR A 133
VAL A 138
LYS A 368
 None
 1.07A 5ecnA-3nzgA:
0.6		 5ecnA-3nzgA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 11 LEU A 294
ASP A 116
LEU A  45
GLY A  44
ALA A 323
 None
 1.31A 5fctA-3nzgA:
undetectable		 5fctA-3nzgA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		3 / 3 TRP A 316
GLU A 339
ASP A 211
 None
GOL  A 601 (-2.6A)
MG  A 507 ( 2.7A)
 1.00A 5gqbA-3nzgA:
6.2		 5gqbA-3nzgA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 LEU A 294
ASP A 116
LEU A  45
GLY A  44
ILE A 320
 None
 0.90A 5j7wD-3nzgA:
undetectable		 5j7wD-3nzgA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		5 / 12 SER A 108
PHE A 105
ARG A 290
TYR A 288
LEU A 374
 None
 1.32A 5ljbA-3nzgA:
undetectable		 5ljbA-3nzgA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		4 / 7 ILE A 229
LEU A 232
TYR A 212
ARG A 215
 None
 0.97A 5xdxA-3nzgA:
undetectable
5xdxJ-3nzgA:
undetectable		 5xdxA-3nzgA:
20.90
5xdxJ-3nzgA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		3 / 3 TYR A  91
ASP A  92
GLN A  95
 None
 0.91A 6g1pA-3nzgA:
undetectable		 6g1pA-3nzgA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3nzg PUTATIVE RACEMASE
(Pseudovibrio
sp.
JE062) 		4 / 7 ILE A 229
LEU A 232
TYR A 212
ARG A 215
 None
 0.87A 6nmpA-3nzgA:
undetectable
6nmpJ-3nzgA:
undetectable		 6nmpA-3nzgA:
20.90
6nmpJ-3nzgA:
10.32