SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nzh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 3nzh 5F6 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 8 GLY H  95
TYR H  97
GLU H  43
SER H  41
 None
 1.08A 1maaD-3nzhH:
undetectable		 1maaD-3nzhH:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 3nzh 5F6 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 6 LEU H 128
ALA H 141
SER H 131
SER H 132
 None
 1.00A 1tz8C-3nzhH:
3.7
1tz8D-3nzhH:
undetectable		 1tz8C-3nzhH:
21.40
1tz8D-3nzhH:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3nzh 5F6 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 6 LEU H 193
GLY H 194
ALA H 129
PRO H 130
 None
 0.41A 3huoA-3nzhH:
undetectable		 3huoA-3nzhH:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3nzh 5F6 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 LEU H  12
ALA H 118
THR H 114
PHE H 150
 None
 1.22A 3vasB-3nzhH:
undetectable		 3vasB-3nzhH:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 3nzh 5F6 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 PRO H 189
SER H 191
SER H 192
 None
 0.47A 6bpyA-3nzhH:
undetectable		 6bpyA-3nzhH:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 3nzh 5F6 HEAVY CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 TYR H  63
GLY H  69
THR H  72
 None
 0.15A 6cjkB-3nzhH:
23.7		 6cjkB-3nzhH:
60.17