SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 5 GLY A 142
GLN A  46
TRP A  47
VAL A  22
 None
 1.17A 1zzuA-3nzmA:
undetectable		 1zzuA-3nzmA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 5 GLY A 142
GLN A  46
TRP A  47
VAL A  22
 None
 1.18A 1zzuB-3nzmA:
undetectable		 1zzuB-3nzmA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A  66
LEU A  60
LEU A  95
ILE A 156
ALA A 157
 None
 1.08A 3a50D-3nzmA:
undetectable		 3a50D-3nzmA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		5 / 11 ALA A 119
ASN A 148
ILE A 156
THR A  41
VAL A  11
 None
 1.13A 3rukD-3nzmA:
undetectable		 3rukD-3nzmA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLY A 142
GLN A  46
TRP A  47
VAL A  22
 None
 1.20A 4kcnB-3nzmA:
0.0		 4kcnB-3nzmA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 6 ARG A  50
GLY A  51
ASP A 140
HIS A  72
 None
None
SNN  A 159 ( 4.9A)
SNN  A 159 ( 3.5A)
 1.22A 4lajA-3nzmA:
undetectable
4lajB-3nzmA:
undetectable		 4lajA-3nzmA:
18.13
4lajB-3nzmA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 5 GLY A 142
GLN A  46
TRP A  47
VAL A  22
 None
 1.20A 5vunA-3nzmA:
undetectable		 5vunA-3nzmA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		4 / 4 GLY A 142
GLN A  46
TRP A  47
VAL A  22
 None
 1.19A 5vuoA-3nzmA:
0.0		 5vuoA-3nzmA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3nzm DNA POLYMERASE III
SUBUNIT ALPHA
(Synechocystis
sp.
PCC
6803) 		3 / 3 GLN A  46
TRP A  47
VAL A  22
 None
 0.98A 6auuA-3nzmA:
undetectable		 6auuA-3nzmA:
16.59