SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nzp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.23A 1a52A-3nzpA:
undetectable		 1a52A-3nzpA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.24A 1a52B-3nzpA:
undetectable		 1a52B-3nzpA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 8 PHE A  93
TYR A  83
VAL A 325
GLY A 322
 None
None
None
PLP  A 701 (-3.3A)
 0.90A 1ekjE-3nzpA:
undetectable
1ekjF-3nzpA:
undetectable		 1ekjE-3nzpA:
16.56
1ekjF-3nzpA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.18A 1ereA-3nzpA:
undetectable		 1ereA-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.18A 1ereB-3nzpA:
undetectable		 1ereB-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.19A 1ereC-3nzpA:
undetectable		 1ereC-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.16A 1ereD-3nzpA:
undetectable		 1ereD-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 11 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.14A 1g50A-3nzpA:
undetectable		 1g50A-3nzpA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 GLY A 322
VAL A 277
ALA A  81
LEU A  85
PHE A  93
 PLP  A 701 (-3.3A)
SO4  A 702 ( 4.1A)
None
None
None
 1.07A 1nw3A-3nzpA:
2.1		 1nw3A-3nzpA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.24A 1pcgA-3nzpA:
undetectable		 1pcgA-3nzpA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.26A 1qkuA-3nzpA:
undetectable		 1qkuA-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.26A 1qkuB-3nzpA:
undetectable		 1qkuB-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.27A 1qkuC-3nzpA:
undetectable		 1qkuC-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 PHE A 444
VAL A 336
ILE A 462
LEU A 511
PHE A 513
 None
 1.04A 1z11C-3nzpA:
undetectable		 1z11C-3nzpA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 GLY A 111
GLU A 115
ASN A 132
 None
None
PLP  A 701 (-3.9A)
 0.66A 1zq9A-3nzpA:
undetectable		 1zq9A-3nzpA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 5 LEU A 332
PRO A 335
ALA A 334
ILE A 333
 None
 1.03A 2aofB-3nzpA:
undetectable		 2aofB-3nzpA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 11 ILE A 319
ALA A 296
PHE A  79
ASN A  61
ILE A  62
 None
 1.26A 2blaA-3nzpA:
undetectable		 2blaA-3nzpA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_D_SPMD1434_1
(NITROALKANE OXIDASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 GLN A 237
VAL A 277
ALA A 276
SER A 321
VAL A 325
 None
SO4  A 702 ( 4.1A)
None
None
None
 1.35A 2c12D-3nzpA:
2.3		 2c12D-3nzpA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 8 GLY A  19
ILE A   6
MET A   1
HIS A 500
 None
 0.90A 2x0pA-3nzpA:
undetectable		 2x0pA-3nzpA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.20A 2yjaB-3nzpA:
undetectable		 2yjaB-3nzpA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 GLY A 205
LEU A 160
ALA A 214
HIS A 231
LEU A 182
 None
None
None
PLP  A 701 (-4.5A)
None
 0.98A 2yqzA-3nzpA:
2.4		 2yqzA-3nzpA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 PHE A 513
PHE A 444
ILE A 462
ASN A 459
 None
 1.16A 2zseA-3nzpA:
undetectable		 2zseA-3nzpA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 LEU A 497
VAL A 442
ILE A 489
LEU A 446
PHE A 513
 None
 1.29A 3fl9D-3nzpA:
undetectable		 3fl9D-3nzpA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 LEU A  49
ARG A  39
SER A 449
GLY A  45
 None
 1.10A 3hcnA-3nzpA:
undetectable		 3hcnA-3nzpA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 LEU A  49
ARG A  39
SER A 449
GLY A  45
 None
 0.96A 3hcrB-3nzpA:
undetectable		 3hcrB-3nzpA:
21.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N2O_A_AG2A1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 HIS A 233
GLY A 235
SER A 236
ASP A 452
LEU A 523
 PLP  A 701 (-3.6A)
None
PLP  A 701 (-2.9A)
None
None
 0.36A 3n2oA-3nzpA:
38.2
3n2oB-3nzpA:
38.2		 3n2oA-3nzpA:
35.82
3n2oB-3nzpA:
35.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N2O_A_AG2A1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 LYS A  86
HIS A 233
GLY A 235
ASP A 452
LEU A 523
 PLP  A 701 (-3.1A)
PLP  A 701 (-3.6A)
None
None
None
 0.80A 3n2oA-3nzpA:
38.2
3n2oB-3nzpA:
38.2		 3n2oA-3nzpA:
35.82
3n2oB-3nzpA:
35.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N2O_B_AG2B1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 HIS A 233
GLY A 235
SER A 236
TYR A 519
LEU A 523
 PLP  A 701 (-3.6A)
None
PLP  A 701 (-2.9A)
PLP  A 701 (-4.2A)
None
 0.28A 3n2oA-3nzpA:
38.2
3n2oB-3nzpA:
38.2		 3n2oA-3nzpA:
35.82
3n2oB-3nzpA:
35.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N2O_B_AG2B1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 LYS A  86
HIS A 233
GLY A 235
TYR A 519
LEU A 523
 PLP  A 701 (-3.1A)
PLP  A 701 (-3.6A)
None
PLP  A 701 (-4.2A)
None
 0.68A 3n2oA-3nzpA:
38.2
3n2oB-3nzpA:
38.2		 3n2oA-3nzpA:
35.82
3n2oB-3nzpA:
35.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 8 LYS A  86
HIS A 233
SER A 236
ASP A 452
LEU A 523
 PLP  A 701 (-3.1A)
PLP  A 701 (-3.6A)
PLP  A 701 (-2.9A)
None
None
 0.67A 3n2oC-3nzpA:
38.2
3n2oD-3nzpA:
38.2		 3n2oC-3nzpA:
35.82
3n2oD-3nzpA:
35.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N2O_D_AG2D1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		7 / 10 LYS A  86
HIS A 233
GLY A 235
ARG A 323
ASP A 452
TYR A 519
LEU A 523
 PLP  A 701 (-3.1A)
PLP  A 701 (-3.6A)
None
None
None
PLP  A 701 (-4.2A)
None
 0.63A 3n2oC-3nzpA:
38.2
3n2oD-3nzpA:
38.2		 3n2oC-3nzpA:
35.82
3n2oD-3nzpA:
35.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 TYR A 104
GLY A 101
VAL A 325
ASP A 316
PHE A 318
 None
 1.27A 3qowA-3nzpA:
undetectable		 3qowA-3nzpA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 ILE A  34
ILE A  31
VAL A 331
LEU A  49
 None
 0.67A 3r9vA-3nzpA:
undetectable
3r9vB-3nzpA:
2.7		 3r9vA-3nzpA:
18.77
3r9vB-3nzpA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 8 HIS A 379
ILE A 382
SER A 381
ILE A 412
 None
 1.07A 3sfeB-3nzpA:
undetectable
3sfeC-3nzpA:
3.0		 3sfeB-3nzpA:
17.80
3sfeC-3nzpA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ASN A  65
ILE A 319
LEU A 275
VAL A 299
GLY A  78
 None
 0.94A 3uq6B-3nzpA:
undetectable		 3uq6B-3nzpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ASN A  65
ILE A 319
LEU A 275
VAL A 299
GLY A  78
 None
 0.89A 3vaqA-3nzpA:
2.4		 3vaqA-3nzpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ASN A  65
ILE A 319
LEU A 275
LEU A 292
GLY A  78
 None
 1.09A 3vaqB-3nzpA:
undetectable		 3vaqB-3nzpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ASN A  65
ILE A 319
LEU A 275
VAL A 299
GLY A  78
 None
 0.95A 3vaqB-3nzpA:
undetectable		 3vaqB-3nzpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ASN A  65
ILE A 319
LEU A 275
LEU A 292
GLY A  78
 None
 1.09A 3vasB-3nzpA:
undetectable		 3vasB-3nzpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 ASN A  65
ILE A 319
LEU A 275
VAL A 299
GLY A  78
 None
 0.92A 3vasB-3nzpA:
undetectable		 3vasB-3nzpA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 LEU A 223
ILE A 129
LEU A 116
ILE A 142
ILE A 145
 None
 1.20A 3zosB-3nzpA:
undetectable		 3zosB-3nzpA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 9 GLY A 273
GLY A 272
ASN A 270
PHE A  66
ILE A  62
 PLP  A 701 (-3.5A)
PLP  A 701 ( 4.2A)
None
None
None
 1.39A 4fgjA-3nzpA:
0.1
4fgjB-3nzpA:
0.7		 4fgjA-3nzpA:
16.69
4fgjB-3nzpA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 5 GLY A 517
ILE A  55
LYS A  57
GLN A  58
 None
None
None
SO4  A 702 ( 4.2A)
 1.04A 4ma8C-3nzpA:
2.8		 4ma8C-3nzpA:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 11 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.21A 4pxmB-3nzpA:
undetectable		 4pxmB-3nzpA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 6 LEU A 557
LEU A 560
GLU A 561
ILE A 570
 None
 0.77A 4ww7A-3nzpA:
undetectable		 4ww7A-3nzpA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 GLU A 314
ILE A 306
LEU A 186
ILE A 269
 None
 0.96A 4xumA-3nzpA:
undetectable		 4xumA-3nzpA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 8 ASP A 401
ASN A 404
ALA A 405
GLU A 361
 None
 0.88A 4zbqA-3nzpA:
2.2		 4zbqA-3nzpA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 11 GLU A 210
LEU A 182
LEU A 206
MET A 261
LEU A 218
 None
 1.33A 4zn7B-3nzpA:
undetectable		 4zn7B-3nzpA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 GLY A 322
LEU A  85
ILE A 319
GLY A 272
GLY A 111
 PLP  A 701 (-3.3A)
None
None
PLP  A 701 ( 4.2A)
None
 1.09A 5d4uA-3nzpA:
undetectable		 5d4uA-3nzpA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 GLY A 322
LEU A  85
ILE A 319
GLY A 272
GLY A 111
 PLP  A 701 (-3.3A)
None
None
PLP  A 701 ( 4.2A)
None
 1.09A 5d4uB-3nzpA:
undetectable		 5d4uB-3nzpA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 LEU A 248
ALA A 251
GLU A 250
LEU A 186
GLY A 272
 None
None
None
None
PLP  A 701 ( 4.2A)
 1.31A 5dxbA-3nzpA:
undetectable		 5dxbA-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 11 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.22A 5dxbB-3nzpA:
undetectable		 5dxbB-3nzpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 8 SER A 188
ALA A 189
PRO A 243
LEU A 244
 None
 1.06A 5dzkd-3nzpA:
undetectable
5dzkr-3nzpA:
undetectable		 5dzkd-3nzpA:
15.69
5dzkr-3nzpA:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 GLY A 274
SER A 321
GLY A 322
ALA A 276
 PLP  A 701 (-4.1A)
None
PLP  A 701 (-3.3A)
None
 0.89A 5e26C-3nzpA:
3.7
5e26D-3nzpA:
2.6		 5e26C-3nzpA:
20.98
5e26D-3nzpA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 PHE A  66
ILE A  62
GLY A 273
GLY A 272
ASN A 270
 None
None
PLP  A 701 (-3.5A)
PLP  A 701 ( 4.2A)
None
 1.42A 5lbtA-3nzpA:
undetectable
5lbtB-3nzpA:
undetectable		 5lbtA-3nzpA:
17.50
5lbtB-3nzpA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 8 HIS A 329
PRO A 451
GLN A 448
GLY A 524
LEU A 523
 None
 1.28A 5w3jB-3nzpA:
undetectable		 5w3jB-3nzpA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 ALA A 251
GLU A 250
LEU A 186
ILE A 238
LEU A 271
 None
 1.22A 6cbzB-3nzpA:
undetectable		 6cbzB-3nzpA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 ASP A 401
ASN A 404
ALA A 405
GLU A 361
 None
 0.89A 6ci6A-3nzpA:
undetectable		 6ci6A-3nzpA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 10 LEU A  38
ASP A  41
ILE A 540
PRO A  29
GLY A 544
 None
 1.20A 6dm0B-3nzpA:
undetectable
6dm0C-3nzpA:
undetectable		 6dm0B-3nzpA:
10.04
6dm0C-3nzpA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 PHE A 514
VAL A  21
ILE A  16
TYR A 440
ILE A 478
 None
 1.04A 6mkeA-3nzpA:
undetectable
6mkeD-3nzpA:
undetectable		 6mkeA-3nzpA:
7.14
6mkeD-3nzpA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3nzp ARGININE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 PHE A 514
VAL A  21
ILE A  16
TYR A 440
ILE A 478
 None
 0.97A 6mkeB-3nzpA:
undetectable
6mkeC-3nzpA:
undetectable		 6mkeB-3nzpA:
7.14
6mkeC-3nzpA:
7.14