SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 12 LEU A  87
LEU A  90
SER A  93
SER A 333
VAL A 138
 None
 1.01A 1db1A-3o01A:
undetectable		 1db1A-3o01A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 12 LEU A  87
LEU A  90
SER A  93
SER A 333
VAL A 138
 None
 0.94A 1ie9A-3o01A:
undetectable		 1ie9A-3o01A:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		4 / 6 PHE A 109
VAL A 138
LEU A  87
SER A 333
 None
 0.94A 1wrlB-3o01A:
undetectable		 1wrlB-3o01A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 12 LEU A  87
ASN A  88
LEU A  90
ALA A  91
LEU A 105
 None
 0.71A 2aa6A-3o01A:
undetectable		 2aa6A-3o01A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		3 / 3 LEU A 245
ASN A 242
ARG A 232
 None
 0.92A 2qhfA-3o01A:
undetectable		 2qhfA-3o01A:
22.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		5 / 9 ASN A 104
ALA A 108
LEU A 318
ASN A 321
VAL A 325
 None
 0.58A 3o01A-3o01A:
39.5
3o01B-3o01A:
34.5		 3o01A-3o01A:
100.00
3o01B-3o01A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		6 / 10 ASN A 104
ALA A 108
LEU A 318
ASN A 321
LEU A 322
VAL A 325
 None
 0.47A 3o02A-3o01A:
38.1
3o02B-3o01A:
33.3		 3o02A-3o01A:
99.68
3o02B-3o01A:
99.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3o01 CELL INVASION
PROTEIN SIPD
(Salmonella
enterica) 		4 / 7 THR A 329
ILE A 330
SER A 333
LEU A  87
 None
 0.71A 5fukA-3o01A:
undetectable
5fukB-3o01A:
undetectable		 5fukA-3o01A:
21.22
5fukB-3o01A:
21.22