SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o0y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 7 LEU A 475
TYR A 556
HIS A 438
THR A 532
 None
SO4  A 610 (-4.2A)
None
None
 1.27A 1afsA-3o0yA:
undetectable		 1afsA-3o0yA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 7 LEU A 475
TYR A 556
HIS A 438
THR A 532
 None
SO4  A 610 (-4.2A)
None
None
 1.26A 1afsB-3o0yA:
undetectable		 1afsB-3o0yA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_1
(DIHYDROFOLATE
REDUCTASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 4 GLU A 478
ASN A 467
ARG A 545
THR A 434
 None
None
SO4  A 610 (-2.7A)
None
 1.34A 1drfA-3o0yA:
0.0		 1drfA-3o0yA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.82A 1j36A-3o0yA:
8.3		 1j36A-3o0yA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.83A 1j36B-3o0yA:
7.7		 1j36B-3o0yA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 11 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.78A 1j37A-3o0yA:
7.8		 1j37A-3o0yA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 11 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.79A 1j37B-3o0yA:
3.5		 1j37B-3o0yA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.78A 1o86A-3o0yA:
3.8		 1o86A-3o0yA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 LEU A 561
LEU A 558
LEU A 475
ILE A 316
HIS A 306
 None
 1.11A 1tw4A-3o0yA:
undetectable		 1tw4A-3o0yA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 LEU A 207
LEU A 145
ALA A 179
ILE A 182
ALA A 257
 None
 1.03A 2bxcA-3o0yA:
undetectable		 2bxcA-3o0yA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.69A 2c6nA-3o0yA:
5.8		 2c6nA-3o0yA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.77A 2c6nB-3o0yA:
7.4		 2c6nB-3o0yA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		3 / 3 LEU A 194
ASN A 192
ARG A 273
 None
 0.92A 2qhfA-3o0yA:
undetectable		 2qhfA-3o0yA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 7 GLY A 328
GLN A 327
PHE A 492
PHE A 347
 TRS  A 612 (-4.6A)
None
None
GOL  A 614 (-4.7A)
 0.91A 2qmzA-3o0yA:
undetectable
2qmzB-3o0yA:
undetectable		 2qmzA-3o0yA:
17.08
2qmzB-3o0yA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 7 GLY A 328
GLN A 327
PHE A 492
PHE A 347
 TRS  A 612 (-4.6A)
None
None
GOL  A 614 (-4.7A)
 1.04A 2qx4A-3o0yA:
undetectable
2qx4B-3o0yA:
undetectable		 2qx4A-3o0yA:
17.08
2qx4B-3o0yA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 6 GLY A 328
GLN A 327
PHE A 492
PHE A 347
 TRS  A 612 (-4.6A)
None
None
GOL  A 614 (-4.7A)
 0.93A 2qx6A-3o0yA:
undetectable
2qx6B-3o0yA:
undetectable		 2qx6A-3o0yA:
17.08
2qx6B-3o0yA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 11 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.72A 2x8zA-3o0yA:
7.9		 2x8zA-3o0yA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.74A 2x91A-3o0yA:
7.8		 2x91A-3o0yA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		3 / 3 TYR A 384
TYR A 404
ILE A 448
 None
 0.81A 3eteA-3o0yA:
undetectable
3eteB-3o0yA:
undetectable		 3eteA-3o0yA:
22.24
3eteB-3o0yA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 GLN A 173
GLN A 156
LEU A  48
THR A  51
LEU A 177
 None
 1.40A 3fsuA-3o0yA:
undetectable		 3fsuA-3o0yA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_E_C2FE995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 11 GLN A 173
GLN A 156
LEU A  48
THR A  51
LEU A 177
 None
 1.40A 3fsuE-3o0yA:
undetectable		 3fsuE-3o0yA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 LEU A 558
GLY A 555
ILE A 305
ALA A 291
ASP A 511
 None
 1.03A 3gwwA-3o0yA:
1.6		 3gwwA-3o0yA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 11 PHE A 116
LEU A  42
PHE A  43
LEU A 460
ILE A 463
 None
 1.49A 3o94D-3o0yA:
undetectable		 3o94D-3o0yA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		3 / 3 ILE A 247
VAL A 221
ARG A 225
 None
 0.51A 3p73A-3o0yA:
undetectable		 3p73A-3o0yA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 GLY A 401
GLY A 431
ALA A 500
PHE A 430
ASN A 427
 None
 0.99A 3qowA-3o0yA:
undetectable		 3qowA-3o0yA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 11 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.80A 4c2pA-3o0yA:
9.9		 4c2pA-3o0yA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 6 PRO A 149
ILE A 181
TYR A 206
TYR A 258
 None
 0.91A 4g10A-3o0yA:
undetectable		 4g10A-3o0yA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 7 ASN A 441
MET A 374
GLU A 369
TYR A 366
 None
 1.31A 4mj8C-3o0yA:
undetectable		 4mj8C-3o0yA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 GLY A 443
GLN A 447
TYR A 556
GLU A 471
ILE A 448
 None
None
SO4  A 610 (-4.2A)
SO4  A 610 ( 4.2A)
None
 1.37A 4pb1A-3o0yA:
undetectable		 4pb1A-3o0yA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 HIS A 438
GLU A 439
HIS A 444
GLU A 471
TYR A 556
 None
SO4  A 610 ( 4.7A)
None
SO4  A 610 ( 4.2A)
SO4  A 610 (-4.2A)
 0.48A 4r7lA-3o0yA:
5.5		 4r7lA-3o0yA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		3 / 3 ASP A 290
ASN A 121
PHE A 116
 None
 0.92A 5jglB-3o0yA:
undetectable		 5jglB-3o0yA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 12 LEU A 207
ALA A 203
LEU A 200
PRO A 195
ILE A 181
 None
 1.17A 5ljcA-3o0yA:
undetectable		 5ljcA-3o0yA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 6 GLU A 344
THR A 330
TYR A 329
PHE A 347
 TRS  A 612 ( 4.5A)
None
TRS  A 612 (-4.1A)
GOL  A 614 (-4.7A)
 1.22A 5lrbA-3o0yA:
undetectable		 5lrbA-3o0yA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 7 GLY A 431
ALA A 500
PHE A 430
ASN A 427
 None
 0.90A 5mvsA-3o0yA:
undetectable		 5mvsA-3o0yA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 8 GLY A 431
ALA A 500
PHE A 430
ASN A 427
 None
 0.90A 5mvsB-3o0yA:
undetectable		 5mvsB-3o0yA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 6 ASN A 590
ASN A 601
ARG A 461
ILE A 100
 None
 1.26A 5uigA-3o0yA:
undetectable		 5uigA-3o0yA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		4 / 5 THR A 244
THR A 235
GLN A 238
ASP A 232
 None
 1.44A 6ecxA-3o0yA:
undetectable		 6ecxA-3o0yA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		3 / 3 LEU A 300
GLN A 304
LYS A 562
 None
 0.88A 6exiB-3o0yA:
undetectable		 6exiB-3o0yA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		3 / 3 LEU A 300
GLN A 304
LYS A 562
 None
 0.88A 6exiA-3o0yA:
undetectable		 6exiA-3o0yA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3o0y LIPOPROTEIN
(Colwellia
psychrerythraea) 		5 / 9 ILE A 141
GLY A 143
LEU A 145
GLY A 125
ASN A 139
 None
 1.18A 6nm4B-3o0yA:
undetectable		 6nm4B-3o0yA:
15.57