SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o12'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3o12 UNCHARACTERIZED
PROTEIN YJL217W
(Saccharomyces
cerevisiae) 		3 / 3 TRP A 115
ALA A  93
VAL A 107
 EDO  A 206 (-3.7A)
None
EDO  A 205 ( 4.9A)
 0.88A 1c4dC-3o12A:
undetectable
1c4dD-3o12A:
undetectable		 1c4dC-3o12A:
5.85
1c4dD-3o12A:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 3o12 UNCHARACTERIZED
PROTEIN YJL217W
(Saccharomyces
cerevisiae) 		5 / 9 SER A 116
SER A 105
ILE A  81
ILE A  85
GLY A  88
 EDO  A 208 (-2.6A)
EDO  A 205 (-2.6A)
None
None
None
 1.07A 3cv9A-3o12A:
undetectable		 3cv9A-3o12A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 3o12 UNCHARACTERIZED
PROTEIN YJL217W
(Saccharomyces
cerevisiae) 		3 / 3 TRP A 115
TRP A  39
THR A  42
 EDO  A 206 (-3.7A)
EDO  A 207 ( 4.0A)
None
 1.26A 4bboB-3o12A:
undetectable		 4bboB-3o12A:
26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 3o12 UNCHARACTERIZED
PROTEIN YJL217W
(Saccharomyces
cerevisiae) 		5 / 9 GLY A 176
ASP A  77
SER A  74
GLY A 175
THR A  32
 None
 1.40A 4lb0A-3o12A:
undetectable		 4lb0A-3o12A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3o12 UNCHARACTERIZED
PROTEIN YJL217W
(Saccharomyces
cerevisiae) 		4 / 8 ARG A  84
PRO A  18
VAL A  21
GLY A  51
 None
 0.94A 4mk4A-3o12A:
undetectable		 4mk4A-3o12A:
24.13