SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o1h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 4 ILE B 187
LEU B 168
VAL B 224
ILE B 164
 None
 0.94A 1fm6D-3o1hB:
undetectable		 1fm6D-3o1hB:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 8 ALA B 240
ASP B 221
ILE B 246
ILE B 223
 None
 0.93A 1p7lC-3o1hB:
undetectable		 1p7lC-3o1hB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 8 ALA B 240
ASP B 221
ILE B 246
ILE B 223
 None
 0.93A 1rg9C-3o1hB:
undetectable		 1rg9C-3o1hB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		5 / 11 GLU B 231
GLY B 225
SER B 254
LEU B 253
ALA B 269
 None
 0.85A 1x7pA-3o1hB:
2.7
1x7pB-3o1hB:
2.9		 1x7pA-3o1hB:
22.41
1x7pB-3o1hB:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		3 / 3 MET B  52
ASN B 120
GLN B  77
 None
TMO  B   1 ( 4.5A)
None
 0.96A 1xoqB-3o1hB:
undetectable		 1xoqB-3o1hB:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		5 / 10 GLY B 225
GLY B 260
LEU B 261
LEU B 253
ALA B 269
 None
 0.92A 2v3kA-3o1hB:
3.2		 2v3kA-3o1hB:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9X_B_PXLB2503_1
(ASPARTATE
AMINOTRANSFERASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		5 / 11 VAL B  53
LEU B  63
THR B 118
VAL B 282
SER B 281
 None
 1.05A 2z9xB-3o1hB:
4.3		 2z9xB-3o1hB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		5 / 12 LEU B 210
GLY B 225
ALA B 229
ALA B 232
LEU B 168
 None
 1.16A 3p5nA-3o1hB:
undetectable		 3p5nA-3o1hB:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		6 / 9 ALA B 165
ASP B 196
ILE B 194
GLY B 225
ILE B 192
ILE B 164
 None
 1.44A 3s43A-3o1hB:
undetectable		 3s43A-3o1hB:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 8 ALA B 240
ASP B 221
ILE B 246
ILE B 223
 None
 0.91A 4kttD-3o1hB:
undetectable		 4kttD-3o1hB:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		5 / 12 TYR B 184
VAL B 251
SER B 226
LEU B 168
SER B 197
 None
 1.48A 4ot2A-3o1hB:
undetectable		 4ot2A-3o1hB:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		5 / 12 ILE B 187
GLY B 148
ALA B 152
TYR B 141
GLU B 185
 None
 1.23A 4xt8A-3o1hB:
undetectable		 4xt8A-3o1hB:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 7 SER B 254
TYR B 252
SER B 250
GLU B 231
 None
 0.89A 4xzkA-3o1hB:
undetectable		 4xzkA-3o1hB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 5 HIS B 155
VAL B 224
GLY B 148
ALA B 147
 None
 1.05A 5hwaA-3o1hB:
undetectable		 5hwaA-3o1hB:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 8 ALA B 240
ASP B 221
ILE B 246
ILE B 223
 None
 0.89A 5t8sA-3o1hB:
undetectable		 5t8sA-3o1hB:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 5 ASP B 272
ILE B 315
ASN B 202
TYR B  44
 None
None
None
TMO  B   1 (-3.7A)
 1.17A 6a93B-3o1hB:
undetectable		 6a93B-3o1hB:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 5 VAL B 138
TRP B 140
PRO B 178
THR B 271
 None
 1.37A 6cduA-3o1hB:
undetectable
6cduB-3o1hB:
undetectable		 6cduA-3o1hB:
20.40
6cduB-3o1hB:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		5 / 7 VAL B 138
TRP B 140
PRO B 178
ILE B 302
THR B 271
 None
 1.25A 6cduF-3o1hB:
undetectable
6cduG-3o1hB:
undetectable		 6cduF-3o1hB:
20.40
6cduG-3o1hB:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 5 VAL B 138
TRP B 140
PRO B 178
THR B 271
 None
 1.36A 6cduI-3o1hB:
undetectable
6cduJ-3o1hB:
undetectable		 6cduI-3o1hB:
20.40
6cduJ-3o1hB:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3o1h PERIPLASMIC PROTEIN
TORT
(Vibrio
parahaemolyticus) 		4 / 5 LEU B 122
THR B  96
THR B 118
GLY B  95
 None
 1.20A 6gtqA-3o1hB:
undetectable		 6gtqA-3o1hB:
21.03