SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3o1l FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A 126
VAL A 130
TYR A 137
ARG A 127
 None
 1.39A 1nw3A-3o1lA:
3.0		 1nw3A-3o1lA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 3o1l FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 SER A  97
HIS A 108
ASP A 134
 None
 0.63A 2wa2B-3o1lA:
2.1		 2wa2B-3o1lA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3o1l FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 HIS A  36
HIS A  49
MET A  47
 None
 0.95A 3mihA-3o1lA:
undetectable		 3mihA-3o1lA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3o1l FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LEU A  24
ILE A   8
MET A  47
PHE A  67
 None
 0.91A 4dc3B-3o1lA:
6.0		 4dc3B-3o1lA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 3o1l FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A 163
VAL A 158
LEU A 175
LEU A 268
ILE A 232
 None
 1.20A 5hv1A-3o1lA:
2.9		 5hv1A-3o1lA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 3o1l FORMYLTETRAHYDROFOLA
TE DEFORMYLASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 VAL A  89
ILE A 188
ALA A 266
LEU A 268
 None
 0.77A 5og9A-3o1lA:
undetectable		 5og9A-3o1lA:
20.66