SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
5 / 12 TYR A 236
ILE A  24
ALA A 241
SER A 239
GLY A 265
NDP  A 312 (-4.7A)
NDP  A 312 (-3.9A)
None
None
None
1.10A 1nbiA-3o26A:
7.4
1nbiA-3o26A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
5 / 12 TYR A 236
ILE A  24
ALA A 241
SER A 239
GLY A 265
NDP  A 312 (-4.7A)
NDP  A 312 (-3.9A)
None
None
None
1.09A 1nbiB-3o26A:
7.2
1nbiB-3o26A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
5 / 12 GLY A  19
ARG A  44
ASP A  70
ASN A  98
ALA A  99
NDP  A 312 (-3.4A)
NDP  A 312 (-3.4A)
NDP  A 312 (-3.2A)
NDP  A 312 (-3.3A)
NDP  A 312 (-3.4A)
1.03A 2bm9E-3o26A:
5.0
2bm9E-3o26A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
3 / 3 GLY A 183
TYR A 187
SER A 184
None
0.76A 2xatA-3o26A:
0.3
2xatA-3o26A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
4 / 8 GLY A 100
ASN A 152
PHE A 104
TYR A 236
NDP  A 312 (-3.6A)
None
None
NDP  A 312 (-4.7A)
1.32A 3ccfA-3o26A:
6.8
3ccfA-3o26A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
3 / 3 THR A 141
LYS A  22
GLU A 143
None
NDP  A 312 (-3.8A)
None
0.99A 3ijdB-3o26A:
2.2
3ijdB-3o26A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
4 / 5 SER A 180
ILE A  24
TYR A 236
GLY A 265
NDP  A 312 ( 4.3A)
NDP  A 312 (-3.9A)
NDP  A 312 (-4.7A)
None
0.80A 3uboB-3o26A:
6.5
3uboB-3o26A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
4 / 6 VAL A  16
LEU A  92
ILE A  85
VAL A 159
None
0.91A 4a9kA-3o26A:
undetectable
4a9kA-3o26A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
5 / 12 GLY A  25
GLY A  20
GLY A  19
ALA A 284
VAL A 267
None
NDP  A 312 ( 4.9A)
NDP  A 312 (-3.4A)
None
NDP  A 312 (-4.1A)
0.84A 4htfB-3o26A:
7.3
4htfB-3o26A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
4 / 4 VAL A 249
THR A 204
GLU A 205
GLU A 206
None
0.94A 4l78A-3o26A:
undetectable
4l78A-3o26A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
5 / 12 ILE A  37
ALA A 291
THR A  18
LEU A 163
LEU A  92
None
1.15A 4qzuC-3o26A:
undetectable
4qzuC-3o26A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum)
4 / 6 ASN A 177
TYR A 246
VAL A 159
THR A 160
None
1.40A 6f32B-3o26A:
4.5
6f32B-3o26A:
23.54