SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o2k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 ARG A 134
GLY A  74
PRO A  75
 None
 0.56A 2hreD-3o2kA:
undetectable		 2hreD-3o2kA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		4 / 7 GLY A 196
ASP A 191
TYR A  61
ARG A 113
 None
DST  A 501 ( 4.1A)
None
DST  A 501 (-2.8A)
 1.33A 3arrA-3o2kA:
undetectable		 3arrA-3o2kA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 SER A 195
GLY A 196
THR A 197
 None
 0.23A 3k9wA-3o2kA:
undetectable		 3k9wA-3o2kA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		4 / 8 THR A 188
LEU A 285
ALA A 143
ALA A 142
 None
 0.86A 3ns1L-3o2kA:
0.2		 3ns1L-3o2kA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 TYR A 450
ARG A 113
SER A 104
 DST  A 501 ( 3.2A)
DST  A 501 (-2.8A)
DST  A 501 ( 4.9A)
 1.08A 4khpI-3o2kA:
undetectable
4khpJ-3o2kA:
undetectable		 4khpI-3o2kA:
15.32
4khpJ-3o2kA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 11 LEU A  68
ALA A  72
PRO A  71
THR A  40
ILE A  43
 None
None
MES  A 475 ( 4.9A)
None
None
 1.30A 4uuuB-3o2kA:
undetectable		 4uuuB-3o2kA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		4 / 6 TYR A 446
ASP A 191
ILE A 112
TYR A 203
 DST  A 501 (-4.7A)
DST  A 501 ( 4.1A)
None
QRP  A 502 ( 3.4A)
 1.28A 5igyA-3o2kA:
undetectable		 5igyA-3o2kA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 LYS A 294
HIS A 366
HIS A 368
 DST  A 501 (-2.9A)
None
None
 0.86A 5oexA-3o2kA:
undetectable		 5oexA-3o2kA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 LYS A 294
HIS A 366
HIS A 368
 DST  A 501 (-2.9A)
None
None
 0.86A 5oexB-3o2kA:
undetectable		 5oexB-3o2kA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 LYS A 294
HIS A 366
HIS A 368
 DST  A 501 (-2.9A)
None
None
 0.86A 5oexC-3o2kA:
undetectable		 5oexC-3o2kA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		3 / 3 LYS A 294
HIS A 366
HIS A 368
 DST  A 501 (-2.9A)
None
None
 0.89A 5oexD-3o2kA:
undetectable		 5oexD-3o2kA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 10 LEU A  96
ALA A 434
PRO A 362
SER A 298
PHE A 280
 QRP  A 502 (-4.3A)
None
None
None
QRP  A 502 (-4.3A)
 1.48A 6b89A-3o2kA:
0.0		 6b89A-3o2kA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 10 LEU A  96
ALA A 434
PRO A 362
SER A 298
PHE A 280
 QRP  A 502 (-4.3A)
None
None
None
QRP  A 502 (-4.3A)
 1.43A 6b89B-3o2kA:
undetectable		 6b89B-3o2kA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 310
MET A 381
PHE A 365
THR A 217
ARG A 248
 None
 1.21A 6baaE-3o2kA:
0.0		 6baaE-3o2kA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 310
MET A 381
PHE A 365
THR A 217
ARG A 248
 None
 1.21A 6baaF-3o2kA:
0.0		 6baaF-3o2kA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 310
MET A 381
PHE A 365
THR A 217
ARG A 248
 None
 1.22A 6baaG-3o2kA:
0.0		 6baaG-3o2kA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o2k BREVIANAMIDE F
PRENYLTRANSFERASE
(Aspergillus
fumigatus) 		5 / 12 ILE A 310
MET A 381
PHE A 365
THR A 217
ARG A 248
 None
 1.22A 6baaH-3o2kA:
0.0		 6baaH-3o2kA:
15.44