SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o2p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)
3o2p CELL DIVISION
CONTROL PROTEIN 53

(Saccharomyces
cerevisiae)
4 / 7 LEU E 743
ASN E 744
LEU E 751
MET E 788
None
1.18A 2w8yA-3o2pE:
undetectable
2w8yA-3o2pE:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3o2p CELL DIVISION
CONTROL PROTEIN 53

(Saccharomyces
cerevisiae)
5 / 12 LEU E 802
LEU E 770
SER E 778
PHE E 782
ILE E 793
None
None
None
None
GOL  E3968 (-3.4A)
1.10A 4x1fA-3o2pE:
undetectable
4x1fA-3o2pE:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3o2p CELL DIVISION
CONTROL PROTEIN 53

(Saccharomyces
cerevisiae)
5 / 12 LEU E 802
LEU E 770
SER E 778
PHE E 782
ILE E 793
None
None
None
None
GOL  E3968 (-3.4A)
1.09A 4x1gA-3o2pE:
undetectable
4x1gA-3o2pE:
16.25