SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o2r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 ILE B 118
ILE B 122
ALA B 121
LEU B  21
PHE B 130
None
1.04A 1xzxX-3o2rB:
undetectable
1xzxX-3o2rB:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 ILE B 118
ILE B 122
ALA B 121
LEU B  21
PHE B 130
None
1.08A 2h79A-3o2rB:
undetectable
2h79A-3o2rB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 LEU B  47
ARG B  71
ILE B  83
ALA B 135
ASP B  48
None
1.24A 3axtA-3o2rB:
undetectable
3axtA-3o2rB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 9 ILE B 118
ILE B 122
LEU B  11
LEU B  21
ALA B  24
None
1.05A 3ozvB-3o2rB:
undetectable
3ozvB-3o2rB:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 ILE B 118
ILE B 122
ALA B 121
LEU B  21
PHE B 130
None
1.11A 3uvvA-3o2rB:
undetectable
3uvvA-3o2rB:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
3 / 3 LYS B 107
PRO B 108
SER B 109
None
0.30A 4k50I-3o2rB:
undetectable
4k50I-3o2rB:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 LEU B  21
LEU B  11
SER B  86
LEU B 115
ILE B 118
None
1.08A 4x1fA-3o2rB:
undetectable
4x1fA-3o2rB:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 LEU B  25
LEU B   7
SER B  86
LEU B 115
ILE B 118
None
1.00A 4x1fA-3o2rB:
undetectable
4x1fA-3o2rB:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 LEU B  21
LEU B  11
SER B  86
LEU B 115
ILE B 118
None
1.05A 4x1gA-3o2rB:
undetectable
4x1gA-3o2rB:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)
3o2r RIBONUCLEASE III
(Campylobacter
jejuni)
5 / 12 LEU B  25
LEU B   7
SER B  86
LEU B 115
ILE B 118
None
1.03A 4x1gA-3o2rB:
undetectable
4x1gA-3o2rB:
23.31