SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 THR A 136
LEU A 140
VAL A 193
THR A 251
 None
 1.02A 1o76B-3o38A:
undetectable		 1o76B-3o38A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 8 THR A 136
LEU A 140
VAL A 193
THR A 251
 None
 1.03A 1uyuB-3o38A:
undetectable		 1uyuB-3o38A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  32
ALA A  26
ASP A  50
VAL A  71
ILE A  48
 None
 0.87A 2avvB-3o38A:
undetectable		 2avvB-3o38A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ASP A  50
ASP A  77
ASN A 104
 None
 0.44A 2bm9D-3o38A:
6.1		 2bm9D-3o38A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  35
ALA A 135
ASN A 103
LEU A  87
 None
 1.06A 2hzqA-3o38A:
undetectable		 2hzqA-3o38A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		3 / 3 LEU A  66
LEU A  68
ARG A  38
 None
 0.76A 3hcnB-3o38A:
2.4		 3hcnB-3o38A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 9 GLY A  32
ALA A  26
ASP A  50
VAL A  71
ILE A  48
 None
 0.95A 3oxvA-3o38A:
undetectable		 3oxvA-3o38A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLY A  32
ALA A  26
ASP A  50
VAL A  71
ILE A  48
 None
 0.97A 3pwmB-3o38A:
undetectable		 3pwmB-3o38A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU A  87
VAL A  84
SER A 131
ALA A 105
SER A  49
 None
 1.42A 4evrA-3o38A:
4.4		 4evrA-3o38A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3o38 SHORT CHAIN
DEHYDROGENASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 THR A  91
LEU A  56
GLN A  62
LEU A  63
 None
 1.21A 4nc3A-3o38A:
undetectable		 4nc3A-3o38A:
21.36