SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o4y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DTL_A_BEPA204_1 (CARDIAC TROPONIN C)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	5 / 11	PHE A 134 ILE A 142 LEU A 147 VAL A 175 MET A 191	None	0.69A	1dtlA-3o4yA: 8.1	1dtlA-3o4yA: 28.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KT3_A_RTLA184_0 (PLASMA RETINOL-BINDING PROTEIN)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	4 / 7	LEU A 40 LEU A 147 MET A 171 LEU A 33	None	1.04A	1kt3A-3o4yA: undetectable	1kt3A-3o4yA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LXF_C_BEPC92_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	6 / 12	PHE A 134 ILE A 142 LEU A 147 ILE A 172 MET A 191 MET A 192	None	1.05A	1lxfC-3o4yA: 5.7	1lxfC-3o4yA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A9E_B_REAB1_1 (RETINOIC ACID RECEPTOR ALPHA)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	5 / 11	PHE A 188 ILE A 45 SER A 123 VAL A 150 LEU A 147	None	1.07A	3a9eB-3o4yA: undetectable	3a9eB-3o4yA: 21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V7P_A_BEZA430_0 (AMIDOHYDROLASE FAMILY PROTEIN)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	4 / 7	GLY A 85 SER A 84 PHE A 112 LEU A 57	None	0.75A	3v7pA-3o4yA: undetectable	3v7pA-3o4yA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RJD_A_TFPA203_1 (CALMODULIN)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	4 / 8	PHE A 134 ILE A 142 LEU A 147 MET A 191	None	0.45A	4rjdA-3o4yA: 8.8	4rjdA-3o4yA: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RJD_B_TFPB203_1 (CALMODULIN)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	4 / 7	PHE A 134 LEU A 147 MET A 191 MET A 192	None	0.51A	4rjdB-3o4yA: 8.6	4rjdB-3o4yA: 18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRX_A_LURA706_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	5 / 12	LEU A 113 LEU A 64 GLY A 80 SER A 84 LEU A 86	None	1.02A	4rrxA-3o4yA: undetectable	4rrxA-3o4yA: 16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RRX_B_LURB706_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3o4y	CALCIUM-DEPENDENT PROTEIN KINASE 3 (Plasmodium vivax)	5 / 12	LEU A 113 LEU A 64 GLY A 80 SER A 84 LEU A 86	None	1.04A	4rrxB-3o4yA: undetectable	4rrxB-3o4yA: 16.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DTL_A_BEPA204_1","CARDIAC TROPONIN C","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",5,"PHE A 134;ILE A 142;LEU A 147;VAL A 175;MET A 191","None","0.69A","1dtlA-3o4yA:8.1","1dtlA-3o4yA:28.92"],["1KT3_A_RTLA184_0","PLASMA RETINOL-BINDING PROTEIN","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",4,"LEU A  40;LEU A 147;MET A 171;LEU A  33","None","1.04A","1kt3A-3o4yA:undetectable","1kt3A-3o4yA:25.00"],["1LXF_C_BEPC92_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",6,"PHE A 134;ILE A 142;LEU A 147;ILE A 172;MET A 191;MET A 192","None","1.05A","1lxfC-3o4yA:5.7","1lxfC-3o4yA:21.50"],["3A9E_B_REAB1_1","RETINOIC ACID RECEPTOR ALPHA","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",5,"PHE A 188;ILE A  45;SER A 123;VAL A 150;LEU A 147","None","1.07A","3a9eB-3o4yA:undetectable","3a9eB-3o4yA:21.20"],["3V7P_A_BEZA430_0","AMIDOHYDROLASE FAMILY PROTEIN","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",4,"GLY A  85;SER A  84;PHE A 112;LEU A  57","None","0.75A","3v7pA-3o4yA:undetectable","3v7pA-3o4yA:17.72"],["4RJD_A_TFPA203_1","CALMODULIN","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",4,"PHE A 134;ILE A 142;LEU A 147;MET A 191","None","0.45A","4rjdA-3o4yA:8.8","4rjdA-3o4yA:18.38"],["4RJD_B_TFPB203_1","CALMODULIN","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",4,"PHE A 134;LEU A 147;MET A 191;MET A 192","None","0.51A","4rjdB-3o4yA:8.6","4rjdB-3o4yA:18.38"],["4RRX_A_LURA706_1","PROSTAGLANDIN G\/H SYNTHASE 2","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",5,"LEU A 113;LEU A  64;GLY A  80;SER A  84;LEU A  86","None","1.02A","4rrxA-3o4yA:undetectable","4rrxA-3o4yA:16.33"],["4RRX_B_LURB706_1","PROSTAGLANDIN G\/H SYNTHASE 2","3o4y","CALCIUM-DEPENDENT PROTEIN KINASE 3","Plasmodium vivax",5,"LEU A 113;LEU A  64;GLY A  80;SER A  84;LEU A  86","None","1.04A","4rrxB-3o4yA:undetectable","4rrxB-3o4yA:16.33"]]