SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o5n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZWP_A_NIMA401_1 (PHOSPHOLIPASE A2 VRV-PL-VIIIA)	3o5n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 (Mus musculus)	4 / 5	LEU A 648 GLY A 697 TRP A 694 ASP A 702	None	1.23A	1zwpA-3o5nA: undetectable	1zwpA-3o5nA: 16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWQ_D_VIAD901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA)	3o5n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 (Mus musculus)	5 / 11	ARG A 725 GLN A 726 ALA A 696 LEU A 660 PHE A 656	None	1.09A	3jwqA-3o5nA: undetectable 3jwqD-3o5nA: undetectable	3jwqA-3o5nA: 11.89 3jwqD-3o5nA: 11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IMS_A_ACTA708_0 (ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL)	3o5n	SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 (Mus musculus)	3 / 3	GLY A 727 GLY A 728 GLN A 649	None	0.49A	5imsA-3o5nA: undetectable	5imsA-3o5nA: 11.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZWP_A_NIMA401_1","PHOSPHOLIPASE A2 VRV-PL-VIIIA","3o5n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3","Mus musculus",4,"LEU A 648;GLY A 697;TRP A 694;ASP A 702","None","1.23A","1zwpA-3o5nA:undetectable","1zwpA-3o5nA:16.00"],["3JWQ_D_VIAD901_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA;CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","3o5n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3","Mus musculus",5,"ARG A 725;GLN A 726;ALA A 696;LEU A 660;PHE A 656","None","1.09A","3jwqA-3o5nA:undetectable;3jwqD-3o5nA:undetectable","3jwqA-3o5nA:11.89;3jwqD-3o5nA:11.89"],["5IMS_A_ACTA708_0","ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL","3o5n","SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3","Mus musculus",3,"GLY A 727;GLY A 728;GLN A 649","None","0.49A","5imsA-3o5nA:undetectable","5imsA-3o5nA:11.33"]]