SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_A_IBPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	3o5t	PII-LIKE PROTEIN PZ (Azospirillum brasilense)	5 / 9	VAL B 63 VAL B 16 LEU B 20 ILE B 91 ALA B 6	ADP B 113 (-4.1A) None None None None	0.96A	1eqgA-3o5tB: undetectable	1eqgA-3o5tB: 10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	3o5t	PII-LIKE PROTEIN PZ (Azospirillum brasilense)	5 / 11	VAL B 63 VAL B 16 LEU B 20 ILE B 91 ALA B 6	ADP B 113 (-4.1A) None None None None	0.97A	1eqgB-3o5tB: undetectable	1eqgB-3o5tB: 10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_A_FLPA701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	3o5t	PII-LIKE PROTEIN PZ (Azospirillum brasilense)	5 / 12	VAL B 63 VAL B 16 LEU B 20 ILE B 91 ALA B 6	ADP B 113 (-4.1A) None None None None	0.96A	1eqhA-3o5tB: undetectable	1eqhA-3o5tB: 10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQH_B_FLPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	3o5t	PII-LIKE PROTEIN PZ (Azospirillum brasilense)	5 / 12	VAL B 63 VAL B 16 LEU B 20 ILE B 91 ALA B 6	ADP B 113 (-4.1A) None None None None	0.97A	1eqhB-3o5tB: undetectable	1eqhB-3o5tB: 10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA825_0 (GEPHYRIN)	3o5t	PII-LIKE PROTEIN PZ (Azospirillum brasilense)	3 / 3	LYS B 2 VAL B 93 ASP B 95	None	0.71A	6fgdA-3o5tB: undetectable	6fgdA-3o5tB: 13.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQG_A_IBPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","3o5t","PII-LIKE PROTEIN PZ","Azospirillum brasilense",5,"VAL B  63;VAL B  16;LEU B  20;ILE B  91;ALA B   6","ADP B 113 (-4.1A);None;None;None;None","0.96A","1eqgA-3o5tB:undetectable","1eqgA-3o5tB:10.69"],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","3o5t","PII-LIKE PROTEIN PZ","Azospirillum brasilense",5,"VAL B  63;VAL B  16;LEU B  20;ILE B  91;ALA B   6","ADP B 113 (-4.1A);None;None;None;None","0.97A","1eqgB-3o5tB:undetectable","1eqgB-3o5tB:10.69"],["1EQH_A_FLPA701_1","PROSTAGLANDIN H2 SYNTHASE-1","3o5t","PII-LIKE PROTEIN PZ","Azospirillum brasilense",5,"VAL B  63;VAL B  16;LEU B  20;ILE B  91;ALA B   6","ADP B 113 (-4.1A);None;None;None;None","0.96A","1eqhA-3o5tB:undetectable","1eqhA-3o5tB:10.69"],["1EQH_B_FLPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","3o5t","PII-LIKE PROTEIN PZ","Azospirillum brasilense",5,"VAL B  63;VAL B  16;LEU B  20;ILE B  91;ALA B   6","ADP B 113 (-4.1A);None;None;None;None","0.97A","1eqhB-3o5tB:undetectable","1eqhB-3o5tB:10.69"],["6FGD_A_ACTA825_0","GEPHYRIN","3o5t","PII-LIKE PROTEIN PZ","Azospirillum brasilense",3,"LYS B   2;VAL B  93;ASP B  95","None","0.71A","6fgdA-3o5tB:undetectable","6fgdA-3o5tB:13.60"]]