SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 179
HIS A 130
LEU A 143
MET A   2
PHE A   4
 None
 1.20A 1d4fD-3o65A:
undetectable		 1d4fD-3o65A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		5 / 10 LEU A  23
SER A  82
LEU A  85
LYS A  86
ARG A 111
 None
 1.30A 2ceoB-3o65A:
undetectable		 2ceoB-3o65A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		5 / 10 LEU A  24
SER A  82
LEU A  85
LYS A  86
ARG A 111
 None
 1.25A 2ceoB-3o65A:
undetectable		 2ceoB-3o65A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		5 / 10 LEU A 170
LEU A  24
SER A  82
LEU A  85
ARG A 111
 None
 1.18A 2ceoB-3o65A:
undetectable		 2ceoB-3o65A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A  24
ASP A 176
PRO A 171
GLY A 168
LEU A  23
 None
 1.12A 2uvnA-3o65A:
undetectable		 2uvnA-3o65A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		4 / 8 CYH A  19
LEU A  85
LEU A  90
VAL A 166
 None
 0.95A 4oj4A-3o65A:
undetectable		 4oj4A-3o65A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		4 / 8 ASN A 133
PHE A 152
PHE A 132
TRP A 131
 None
 1.49A 4v2zC-3o65A:
undetectable		 4v2zC-3o65A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 PHE A 127
LYS A   1
ILE A   5
PHE A 132
ASN A 133
 None
 1.34A 5hgcA-3o65A:
undetectable		 5hgcA-3o65A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		4 / 6 PHE A 113
VAL A 165
TYR A 100
ILE A 105
 None
 1.30A 5iwuA-3o65A:
undetectable		 5iwuA-3o65A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 GLY A 128
LEU A 179
HIS A 130
 None
 0.67A 5u63A-3o65A:
undetectable		 5u63A-3o65A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 GLY A 128
LEU A 179
HIS A 130
 None
 0.64A 5u63B-3o65A:
undetectable		 5u63B-3o65A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 ALA A 150
PHE A  95
GLN A 101
 None
 0.84A 6eceA-3o65A:
undetectable		 6eceA-3o65A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3o65 PUTATIVE
ATAXIN-3-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 ALA A 154
PHE A  95
GLN A 101
 None
 0.74A 6eceA-3o65A:
undetectable		 6eceA-3o65A:
20.45