SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 VAL A   5
GLY A   4
LEU A   3
GLY A 232
LEU A 254
 None
None
None
PO4  A 301 (-3.6A)
None
 1.07A 1fduA-3o6cA:
undetectable		 1fduA-3o6cA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 7 ILE A  75
LEU A  78
THR A  39
LEU A  40
 None
 0.93A 1v55A-3o6cA:
undetectable
1v55J-3o6cA:
undetectable		 1v55A-3o6cA:
18.76
1v55J-3o6cA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 10 ALA A  79
LEU A  80
LEU A 117
ALA A 120
VAL A 124
 None
 0.97A 2bxgB-3o6cA:
undetectable		 2bxgB-3o6cA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 9 ASP A  51
HIS A  41
GLU A  92
HIS A  48
LEU A  67
 None
None
None
PO4  A 302 (-3.9A)
None
 1.48A 2jihA-3o6cA:
undetectable		 2jihA-3o6cA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 6 LEU A  71
ASN A  66
GLN A 144
ILE A 114
 None
 1.24A 2jn3A-3o6cA:
undetectable		 2jn3A-3o6cA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 6 ILE A  57
PRO A  22
LEU A 244
ILE A  10
 None
 1.00A 2q83B-3o6cA:
undetectable		 2q83B-3o6cA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ILE A 226
VAL A 220
GLU A 188
LEU A 194
VAL A 206
 None
 1.19A 3fpjB-3o6cA:
undetectable		 3fpjB-3o6cA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ILE A  38
VAL A  31
ASP A  23
ILE A  10
ALA A  11
 None
 1.06A 5lg3A-3o6cA:
undetectable		 5lg3A-3o6cA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ILE A  38
VAL A  31
ASP A  23
ILE A  10
ALA A  11
 None
 1.05A 5lg3E-3o6cA:
undetectable		 5lg3E-3o6cA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		3 / 3 HIS A 152
ASN A 155
ALA A 159
 None
 0.27A 5n4tB-3o6cA:
undetectable		 5n4tB-3o6cA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 LEU A  71
VAL A  90
LEU A 103
LEU A  76
LEU A  67
 None
 0.93A 5og9B-3o6cA:
undetectable		 5og9B-3o6cA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		5 / 12 HIS A  48
LEU A  54
LEU A  24
ILE A   7
ALA A  11
 PO4  A 302 (-3.9A)
None
None
None
None
 1.45A 5xprA-3o6cA:
undetectable		 5xprA-3o6cA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 7 ILE A  75
LEU A  78
THR A  39
LEU A  40
 None
 0.99A 6nmfA-3o6cA:
undetectable
6nmfJ-3o6cA:
undetectable		 6nmfA-3o6cA:
18.76
6nmfJ-3o6cA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE
(Campylobacter
jejuni) 		4 / 7 ILE A  75
LEU A  78
THR A  39
LEU A  40
 None
 0.93A 6nmpA-3o6cA:
undetectable
6nmpJ-3o6cA:
undetectable		 6nmpA-3o6cA:
18.76
6nmpJ-3o6cA:
16.94