SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PK4_A_ACAA100_1 (HUMAN PLASMINOGEN KRINGLE 4)	3o6f	HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN (Homo sapiens)	4 / 7	LYS B 100 ASP B 57 ARG B 9 TRP B 90	None	1.22A	2pk4A-3o6fB: undetectable	2pk4A-3o6fB: 15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBM_A_CAMA517_0 (CYTOCHROME P450-CAM)	3o6f	HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN (Homo sapiens)	4 / 8	PHE B 151 THR B 174 VAL B 158 ILE B 156	None	0.75A	2qbmA-3o6fB: undetectable	2qbmA-3o6fB: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MJR_D_AC2D601_1 (DEOXYCYTIDINE KINASE)	3o6f	HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN (Homo sapiens)	4 / 8	GLU B 43 GLN B 39 ARG B 58 PHE B 60	None	0.95A	3mjrD-3o6fB: undetectable	3mjrD-3o6fB: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IAO_A_URFA301_1 (BIFUNCTIONAL PROTEIN PYRR)	3o6f	HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN (Homo sapiens)	4 / 4	ARG B 68 ASP B 70 HIS B 45 ARG B 58	None	1.47A	5iaoA-3o6fB: 0.0	5iaoA-3o6fB: 20.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2PK4_A_ACAA100_1","HUMAN PLASMINOGEN KRINGLE 4","3o6f","HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN","Homo sapiens",4,"LYS B 100;ASP B  57;ARG B   9;TRP B  90","None","1.22A","2pk4A-3o6fB:undetectable","2pk4A-3o6fB:15.42"],["2QBM_A_CAMA517_0","CYTOCHROME P450-CAM","3o6f","HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN","Homo sapiens",4,"PHE B 151;THR B 174;VAL B 158;ILE B 156","None","0.75A","2qbmA-3o6fB:undetectable","2qbmA-3o6fB:20.30"],["3MJR_D_AC2D601_1","DEOXYCYTIDINE KINASE","3o6f","HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN","Homo sapiens",4,"GLU B  43;GLN B  39;ARG B  58;PHE B  60","None","0.95A","3mjrD-3o6fB:undetectable","3mjrD-3o6fB:19.86"],["5IAO_A_URFA301_1","BIFUNCTIONAL PROTEIN PYRR","3o6f","HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DRB1-4 BETA CHAIN","Homo sapiens",4,"ARG B  68;ASP B  70;HIS B  45;ARG B  58","None","1.47A","5iaoA-3o6fB:0.0","5iaoA-3o6fB:20.17"]]