SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3o6q STAGE II SPORULATION
PROTEIN SA
(Bacillus
subtilis) 		4 / 5 TYR A 211
LEU A 186
THR A 165
ARG A 171
 None
 1.36A 1i2wA-3o6qA:
undetectable		 1i2wA-3o6qA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3o6q STAGE II SPORULATION
PROTEIN SA
(Bacillus
subtilis) 		4 / 7 GLU A 105
GLU A 108
GLU A 104
GLU A 101
 None
 1.11A 1knyA-3o6qA:
undetectable
1knyB-3o6qA:
undetectable		 1knyA-3o6qA:
22.67
1knyB-3o6qA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3o6q STAGE II SPORULATION
PROTEIN SA
(Bacillus
subtilis) 		4 / 8 GLU A 101
GLU A 105
GLU A 108
GLU A 104
 None
 0.99A 1knyA-3o6qA:
undetectable
1knyB-3o6qA:
undetectable		 1knyA-3o6qA:
22.67
1knyB-3o6qA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3o6q STAGE II SPORULATION
PROTEIN SA
(Bacillus
subtilis) 		5 / 11 VAL A 200
LEU A 156
LEU A 232
THR A 222
TYR A 120
 None
 1.32A 1mmtA-3o6qA:
undetectable		 1mmtA-3o6qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3o6q STAGE II SPORULATION
PROTEIN SA
(Bacillus
subtilis) 		4 / 4 ILE A 220
SER A 219
ASP A 194
ASP A 177
 None
 0.95A 4krhB-3o6qA:
undetectable		 4krhB-3o6qA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 3o6q STAGE II SPORULATION
PROTEIN SB
(Bacillus
subtilis) 		3 / 3 VAL B  33
SER B  34
THR B  37
 None
 0.47A 4luhA-3o6qB:
undetectable		 4luhA-3o6qB:
6.86