SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o7j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.34A 1a52A-3o7jA:
undetectable		 1a52A-3o7jA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.34A 1a52B-3o7jA:
undetectable		 1a52B-3o7jA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.31A 1gwrA-3o7jA:
undetectable		 1gwrA-3o7jA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 9 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.30A 1gwrB-3o7jA:
undetectable		 1gwrB-3o7jA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		3 / 3 PHE A   7
LEU A  19
MET A 157
 None
 0.87A 1mx1D-3o7jA:
undetectable		 1mx1D-3o7jA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		6 / 12 PHE A   7
ASN A   8
THR A  47
LEU A  45
LEU A  32
PHE A  38
 None
 1.40A 1og5A-3o7jA:
undetectable		 1og5A-3o7jA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.35A 1pcgB-3o7jA:
undetectable		 1pcgB-3o7jA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.46A 1qkuA-3o7jA:
undetectable		 1qkuA-3o7jA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.46A 1qkuB-3o7jA:
undetectable		 1qkuB-3o7jA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.46A 1qkuC-3o7jA:
undetectable		 1qkuC-3o7jA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 12 GLU A 161
LEU A  45
ARG A  49
ARG A 159
GLU A  87
 None
None
None
None
2AL  A 451 (-3.7A)
 1.47A 2htuA-3o7jA:
undetectable		 2htuA-3o7jA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.31A 3erdB-3o7jA:
undetectable		 3erdB-3o7jA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 12 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.31A 4j24C-3o7jA:
undetectable		 4j24C-3o7jA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 12 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.31A 4j26B-3o7jA:
undetectable		 4j26B-3o7jA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		4 / 7 ARG A 124
GLN A 151
GLU A 147
ARG A 135
 None
 1.10A 4mv7A-3o7jA:
undetectable		 4mv7A-3o7jA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 11 LEU A  64
GLY A 114
GLU A 110
LEU A  60
ALA A 148
 None
 1.14A 4wnuA-3o7jA:
undetectable		 4wnuA-3o7jA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 11 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.31A 4zn7B-3o7jA:
undetectable		 4zn7B-3o7jA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 11 GLN A   6
LEU A  10
PHE A   7
LEU A   4
ALA A   3
 None
 1.16A 5ji0A-3o7jA:
undetectable		 5ji0A-3o7jA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 9 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.37A 5wgqA-3o7jA:
undetectable		 5wgqA-3o7jA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		5 / 10 GLU A 161
LEU A 158
ARG A  49
HIS A  80
LEU A  83
 None
 1.36A 5wgqB-3o7jA:
undetectable		 5wgqB-3o7jA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3o7j OHCU DECARBOXYLASE
(Klebsiella
pneumoniae) 		3 / 3 HIS A  67
ARG A 159
ILE A 155
 None
None
2AL  A 451 (-4.1A)
 0.87A 6fgdA-3o7jA:
undetectable		 6fgdA-3o7jA:
17.96