SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_B_ADNB2604_1
(5'-NUCLEOTIDASE)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 10 ASN A 162
SER A 362
GLY A 311
PHE A 309
GLY A 315
 BNG  A 439 (-2.9A)
None
None
None
None
 1.46A 1ho5B-3o7qA:
undetectable		 1ho5B-3o7qA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 12 PHE A 422
TYR A 270
ALA A 335
LEU A 338
THR A 304
 None
 1.25A 1mx8A-3o7qA:
undetectable		 1mx8A-3o7qA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 11 LEU A 204
ALA A 111
VAL A 181
LEU A 178
LEU A  48
 None
 1.06A 1rlbF-3o7qA:
undetectable		 1rlbF-3o7qA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 9 ASN A 139
ILE A 387
ALA A 263
VAL A 264
PHE A 386
 None
 1.00A 2drdA-3o7qA:
2.3		 2drdA-3o7qA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 11 LEU A 145
ILE A  25
PHE A  28
ALA A  29
LEU A 157
 None
 1.35A 2v0mA-3o7qA:
undetectable		 2v0mA-3o7qA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 11 LEU A 145
ILE A  25
PHE A  28
ALA A  29
LEU A 157
 None
 1.20A 2v0mD-3o7qA:
undetectable		 2v0mD-3o7qA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 12 ASP A  46
GLY A 165
SER A 163
ASN A 162
GLN A 159
 None
None
None
BNG  A 439 (-2.9A)
BNG  A 439 ( 4.4A)
 1.35A 2ycjA-3o7qA:
undetectable		 2ycjA-3o7qA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 12 ILE A 226
GLY A  93
GLY A  97
ALA A 223
ALA A  81
 None
 1.06A 2yvlD-3o7qA:
undetectable		 2yvlD-3o7qA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 12 ILE A  77
GLY A  97
ALA A 129
LEU A 131
ILE A 226
 None
 0.90A 3mb5A-3o7qA:
undetectable		 3mb5A-3o7qA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		3 / 3 TYR A 382
GLY A 245
ASP A 241
 None
 0.69A 3ou6C-3o7qA:
undetectable		 3ou6C-3o7qA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_B_C2FB302_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 12 ASP A  46
GLY A 165
SER A 163
ASN A 162
GLN A 159
 None
None
None
BNG  A 439 (-2.9A)
BNG  A 439 ( 4.4A)
 1.09A 4djeB-3o7qA:
undetectable		 4djeB-3o7qA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		4 / 5 ASP A  46
ASN A  45
ILE A 127
VAL A 219
 None
 1.25A 4hytA-3o7qA:
undetectable		 4hytA-3o7qA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 12 ILE A 226
VAL A 142
GLY A  93
PHE A 231
LEU A 134
 None
None
None
None
BNG  A 439 ( 4.3A)
 1.15A 5byjA-3o7qA:
undetectable		 5byjA-3o7qA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		5 / 12 ILE A 257
ALA A 255
GLY A 377
SER A 250
GLY A 372
 None
 1.24A 5i75A-3o7qA:
undetectable		 5i75A-3o7qA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		4 / 8 ALA A 298
THR A 302
THR A 304
ALA A 166
 None
 0.84A 5x2tI-3o7qA:
undetectable
5x2tJ-3o7qA:
undetectable
5x2tK-3o7qA:
undetectable
5x2tL-3o7qA:
undetectable		 5x2tI-3o7qA:
14.35
5x2tJ-3o7qA:
16.58
5x2tK-3o7qA:
14.35
5x2tL-3o7qA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3o7q L-FUCOSE-PROTON
SYMPORTER
(Escherichia
coli) 		4 / 5 ILE A 127
PHE A 108
ASN A  60
TYR A 117
 None
 1.24A 6a93B-3o7qA:
undetectable		 6a93B-3o7qA:
22.78