SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		5 / 11 ASP A  48
GLY A  63
GLY A  62
PHE A  51
PHE A   6
 None
 0.72A 1w76A-3o7tA:
undetectable		 1w76A-3o7tA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 6 LEU A 134
ASN A   3
LYS A  92
ILE A 112
 None
 1.23A 2jn3A-3o7tA:
undetectable		 2jn3A-3o7tA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 6 PHE A  20
PHE A  34
GLY A  62
GLY A  63
 None
 0.91A 2qr2A-3o7tA:
undetectable
2qr2B-3o7tA:
undetectable		 2qr2A-3o7tA:
24.14
2qr2B-3o7tA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 5 GLY A  62
GLY A  63
PHE A  20
PHE A  34
 None
 0.84A 2qr2A-3o7tA:
undetectable
2qr2B-3o7tA:
undetectable		 2qr2A-3o7tA:
24.14
2qr2B-3o7tA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 8 PHE A  20
PHE A  34
GLY A  62
ILE A  50
 None
 0.88A 2qwxA-3o7tA:
undetectable
2qwxB-3o7tA:
undetectable		 2qwxA-3o7tA:
23.61
2qwxB-3o7tA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 6 PHE A  20
PHE A  34
GLY A  62
GLY A  63
 None
 0.79A 2qx6A-3o7tA:
undetectable
2qx6B-3o7tA:
undetectable		 2qx6A-3o7tA:
24.14
2qx6B-3o7tA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 7 ILE A 112
ASP A 135
LEU A 134
GLY A 133
 None
 0.73A 2tsrA-3o7tA:
undetectable		 2tsrA-3o7tA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.35A 2y69C-3o7tA:
undetectable
2y69J-3o7tA:
undetectable		 2y69C-3o7tA:
18.39
2y69J-3o7tA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.38A 3abmC-3o7tA:
undetectable
3abmJ-3o7tA:
undetectable		 3abmC-3o7tA:
18.39
3abmJ-3o7tA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.36A 3abmP-3o7tA:
undetectable
3abmW-3o7tA:
undetectable		 3abmP-3o7tA:
18.39
3abmW-3o7tA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.35A 3ag3C-3o7tA:
undetectable
3ag3J-3o7tA:
undetectable		 3ag3C-3o7tA:
18.39
3ag3J-3o7tA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 6 THR A 117
SER A  97
LEU A  95
THR A 113
 None
 0.89A 3deuB-3o7tA:
undetectable		 3deuB-3o7tA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		5 / 11 PHE A  20
PHE A  34
GLY A  62
GLY A  63
ILE A  50
 None
 0.99A 3owxA-3o7tA:
undetectable
3owxB-3o7tA:
undetectable		 3owxA-3o7tA:
23.61
3owxB-3o7tA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		5 / 12 GLY A  62
GLY A  63
ILE A  50
PHE A  20
PHE A  34
 None
 0.95A 4fglA-3o7tA:
undetectable
4fglB-3o7tA:
undetectable		 4fglA-3o7tA:
23.40
4fglB-3o7tA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 7 ILE A 112
ASP A 135
LEU A 134
GLY A 133
 None
 0.84A 4iqqA-3o7tA:
undetectable		 4iqqA-3o7tA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 7 ILE A 112
ASP A 135
LEU A 134
GLY A 133
 None
 0.70A 4iqqC-3o7tA:
undetectable		 4iqqC-3o7tA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 8 ILE A 112
ASP A 135
LEU A 134
GLY A 133
 None
 0.81A 4iqqD-3o7tA:
undetectable		 4iqqD-3o7tA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 8 PHE A  20
PHE A  34
GLY A  62
ILE A  50
 None
 0.88A 4qogA-3o7tA:
undetectable
4qogB-3o7tA:
undetectable		 4qogA-3o7tA:
23.61
4qogB-3o7tA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 8 PHE A  20
PHE A  34
GLY A  62
ILE A  50
 None
 0.87A 4qoiA-3o7tA:
undetectable
4qoiB-3o7tA:
undetectable		 4qoiA-3o7tA:
23.61
4qoiB-3o7tA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		5 / 11 GLY A  62
GLY A  63
ILE A  50
PHE A  20
PHE A  34
 None
 0.95A 4qoiA-3o7tA:
undetectable
4qoiB-3o7tA:
undetectable		 4qoiA-3o7tA:
23.61
4qoiB-3o7tA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 7 GLY A  63
GLN A 109
SER A  49
HIS A  52
 None
 1.14A 4ws0A-3o7tA:
undetectable		 4ws0A-3o7tA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		5 / 12 GLY A  62
GLY A  63
ILE A  50
PHE A  20
PHE A  34
 None
 0.77A 4zvmA-3o7tA:
undetectable
4zvmB-3o7tA:
undetectable		 4zvmA-3o7tA:
24.14
4zvmB-3o7tA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		5 / 12 GLY A 107
ILE A  76
ASN A 100
PHE A  34
LEU A  96
 None
 1.04A 5fa8A-3o7tA:
undetectable		 5fa8A-3o7tA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 6 ILE A 112
ASP A 135
LEU A 134
GLY A 133
 None
 0.82A 5x5qE-3o7tA:
undetectable		 5x5qE-3o7tA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.32A 5xdqC-3o7tA:
undetectable
5xdqJ-3o7tA:
undetectable		 5xdqC-3o7tA:
18.39
5xdqJ-3o7tA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3o7t CYCLOPHILIN A
(Moniliophthora
perniciosa) 		4 / 5 ARG A  35
PHE A 110
PHE A 127
LEU A  22
 None
 1.34A 5xdqP-3o7tA:
undetectable
5xdqW-3o7tA:
undetectable		 5xdqP-3o7tA:
18.39
5xdqW-3o7tA:
16.88