SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3o7v PIWI-LIKE PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE X 295
PHE X 282
LEU X 362
VAL X 319
VAL X 279
 None
 1.38A 1q23C-3o7vX:
undetectable		 1q23C-3o7vX:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3o7v PIWI-LIKE PROTEIN 1
(Homo
sapiens) 		4 / 8 TYR X 350
TYR X 345
SER X 341
ILE X 354
 C  A  12 ( 4.4A)
None
None
None
 1.13A 2xz5B-3o7vX:
undetectable
2xz5E-3o7vX:
undetectable		 2xz5B-3o7vX:
20.64
2xz5E-3o7vX:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3o7v PIWI-LIKE PROTEIN 1
(Homo
sapiens) 		4 / 8 TYR X 350
TYR X 345
SER X 341
ILE X 383
 C  A  12 ( 4.4A)
None
None
None
 1.06A 2xz5B-3o7vX:
undetectable
2xz5E-3o7vX:
undetectable		 2xz5B-3o7vX:
20.64
2xz5E-3o7vX:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3o7v PIWI-LIKE PROTEIN 1
(Homo
sapiens) 		5 / 10 PHE X 295
PHE X 282
LEU X 362
VAL X 319
VAL X 279
 None
 1.46A 3u9fI-3o7vX:
undetectable		 3u9fI-3o7vX:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3o7v PIWI-LIKE PROTEIN 1
(Homo
sapiens) 		5 / 10 PHE X 295
PHE X 282
LEU X 362
VAL X 319
VAL X 279
 None
 1.38A 3u9fR-3o7vX:
undetectable		 3u9fR-3o7vX:
19.72