SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		5 / 10 CYH A  70
GLY A 102
LEU A 107
VAL A 111
ALA A  39
 None
 1.19A 1fpqA-3o85A:
undetectable		 1fpqA-3o85A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		5 / 12 ILE A 101
ALA A  99
ALA A  39
VAL A 110
ILE A 114
 None
 1.07A 3e00A-3o85A:
undetectable		 3e00A-3o85A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		5 / 12 LEU A  19
ASP A   4
ILE A  60
PRO A  67
LEU A  64
 None
 1.12A 3eeoA-3o85A:
undetectable		 3eeoA-3o85A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		5 / 10 ILE A 101
ALA A  99
ALA A  39
VAL A 110
ILE A 114
 None
 1.08A 3falA-3o85A:
undetectable		 3falA-3o85A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		4 / 7 GLY A  26
ALA A  27
VAL A  92
ILE A  52
 None
 0.72A 3t3cA-3o85A:
undetectable		 3t3cA-3o85A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		5 / 12 VAL A  92
LEU A 107
VAL A  23
GLY A  26
ALA A  27
 None
 0.87A 5iktA-3o85A:
undetectable		 5iktA-3o85A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		5 / 12 VAL A  92
LEU A 107
VAL A  23
GLY A  26
ALA A  27
 None
 0.90A 5iktB-3o85A:
undetectable		 5iktB-3o85A:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		4 / 7 HIS A 104
HIS A  25
LEU A  22
SER A  28
 None
 1.00A 5m8rA-3o85A:
undetectable		 5m8rA-3o85A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3o85 RIBOSOMAL PROTEIN
L7AE
(Giardia
intestinalis) 		4 / 8 HIS A 104
HIS A  25
LEU A  22
SER A  28
 None
 1.01A 5m8rD-3o85A:
undetectable		 5m8rD-3o85A:
13.26