SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o8q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 6 PRO B 147
GLN B 145
LYS B 140
VAL B 138
 None
 1.29A 1l2iB-3o8qB:
undetectable		 1l2iB-3o8qB:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 12 THR B 224
GLY B 220
ASN B 227
ILE B 189
LEU B 128
 None
 1.14A 1r30A-3o8qB:
undetectable		 1r30A-3o8qB:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 12 THR B 224
GLY B 220
ASN B 227
ILE B 189
LEU B 128
 None
 1.14A 1r30B-3o8qB:
undetectable		 1r30B-3o8qB:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 11 THR B 153
ILE B 129
PHE B 208
PRO B 201
ILE B 207
 None
 1.19A 2y7kA-3o8qB:
3.1		 2y7kA-3o8qB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1304_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 10 THR B 153
ILE B 129
PHE B 208
PRO B 201
ILE B 207
 None
 1.16A 2y7kB-3o8qB:
1.5		 2y7kB-3o8qB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 12 THR B 153
ILE B 129
PHE B 208
PRO B 201
ILE B 207
 None
 1.25A 2y7kC-3o8qB:
3.5		 2y7kC-3o8qB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 10 THR B 153
ILE B 129
PHE B 208
PRO B 201
ILE B 207
 None
 1.24A 2y7pA-3o8qB:
3.1		 2y7pA-3o8qB:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 12 ILE B 150
VAL B 111
GLY B 107
LEU B  85
LEU B 163
 None
 1.04A 3em0B-3o8qB:
undetectable		 3em0B-3o8qB:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 4 LEU B 139
MET B 244
ILE B 207
ASP B 186
 None
 1.41A 3hecA-3o8qB:
undetectable		 3hecA-3o8qB:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 8 PHE B  11
VAL B  64
VAL B  42
ILE B 100
 None
 0.85A 3hjoA-3o8qB:
undetectable		 3hjoA-3o8qB:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 8 PHE B  11
VAL B  64
VAL B  42
ILE B 100
 None
 0.87A 3hjoB-3o8qB:
undetectable		 3hjoB-3o8qB:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 11 TYR B  73
GLY B 102
GLY B  61
PHE B  11
ALA B  51
 None
 1.10A 3sufC-3o8qB:
undetectable		 3sufC-3o8qB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 8 GLN B 112
GLN B 118
ILE B 239
VAL B 213
 None
 0.93A 4dx7B-3o8qB:
undetectable		 4dx7B-3o8qB:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 6 ASP B 240
ASN B 227
ALA B 238
ASP B 113
 None
 1.21A 4mdbA-3o8qB:
undetectable		 4mdbA-3o8qB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 12 ASN B  90
ALA B 250
GLY B 247
ILE B 266
GLY B 262
 None
 1.22A 4obwA-3o8qB:
2.2		 4obwA-3o8qB:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 5 ILE B 266
GLY B 243
ILE B  23
LEU B 267
 None
 0.91A 5dzkd-3o8qB:
undetectable
5dzkk-3o8qB:
undetectable
5dzky-3o8qB:
undetectable		 5dzkd-3o8qB:
20.43
5dzkk-3o8qB:
21.20
5dzky-3o8qB:
0.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 12 PHE B 226
ALA B 230
ILE B 150
TYR B 185
ILE B 207
 None
 0.86A 5h8tA-3o8qB:
undetectable		 5h8tA-3o8qB:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 8 ARG B  82
GLY B 102
THR B  80
ASN B  90
 None
 1.03A 5hwaA-3o8qB:
undetectable		 5hwaA-3o8qB:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		5 / 12 VAL B 138
ILE B 126
LEU B 142
GLY B 107
LEU B 181
 None
 1.10A 5ienA-3o8qB:
undetectable		 5ienA-3o8qB:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA
(Vibrio
cholerae) 		4 / 8 ILE B  23
GLN B 248
THR B 105
GLU B 108
 None
 1.17A 6fbvC-3o8qB:
undetectable		 6fbvC-3o8qB:
12.77