SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o8s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJT_A_SAMA501_1 (N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE)	3o8s	ADP-RIBOSE PYROPHOSPHATASE (Streptococcus suis)	3 / 3	ARG A 125 ASP A 80 ASP A 173	ACT A 211 (-3.4A) None None	0.85A	2ejtA-3o8sA: undetectable	2ejtA-3o8sA: 19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_C_QDNC602_1 (CYTOCHROME P450 2D6)	3o8s	ADP-RIBOSE PYROPHOSPHATASE (Streptococcus suis)	5 / 11	GLY A 118 LEU A 119 GLU A 157 ALA A 166 SER A 167	None EDO A 207 (-4.3A) None None EDO A 207 (-2.6A)	1.33A	4wnuC-3o8sA: undetectable	4wnuC-3o8sA: 17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB603_1 (PHIAB6 TAILSPIKE)	3o8s	ADP-RIBOSE PYROPHOSPHATASE (Streptococcus suis)	3 / 3	VAL A 147 GLU A 116 GLU A 112	None EDO A 210 (-3.7A) None	0.85A	5jsdB-3o8sA: undetectable 5jsdC-3o8sA: undetectable	5jsdB-3o8sA: 14.06 5jsdC-3o8sA: 14.06