SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3o9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 402
GLN A 393
HIS A 369
TYR A 272
 MHI  A 516 (-2.8A)
None
None
None
 1.33A 1nx9A-3o9pA:
undetectable		 1nx9A-3o9pA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 402
GLN A 393
HIS A 369
TYR A 272
 MHI  A 516 (-2.8A)
None
None
None
 1.30A 1nx9B-3o9pA:
undetectable		 1nx9B-3o9pA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 402
GLN A 393
HIS A 369
TYR A 272
 MHI  A 516 (-2.8A)
None
None
None
 1.30A 1nx9C-3o9pA:
undetectable		 1nx9C-3o9pA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 8 ARG A 402
GLN A 393
HIS A 369
TYR A 272
 MHI  A 516 (-2.8A)
None
None
None
 1.31A 1nx9D-3o9pA:
undetectable		 1nx9D-3o9pA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 12 TYR A 273
LEU A 361
LEU A 362
ILE A 372
ILE A 436
 None
 0.99A 1tw4B-3o9pA:
undetectable		 1tw4B-3o9pA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 10 LEU A 158
PHE A 164
LEU A 152
LEU A 148
ILE A 118
 None
 0.98A 2bxeB-3o9pA:
2.1		 2bxeB-3o9pA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 359
ILE A 374
ILE A 295
VAL A 386
VAL A 388
 None
 0.78A 2nnkB-3o9pA:
undetectable		 2nnkB-3o9pA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 11 LEU A 359
ILE A 374
ILE A 295
VAL A 386
VAL A 388
 None
 0.93A 2nnpB-3o9pA:
undetectable		 2nnpB-3o9pA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 THR A 316
THR A 429
HIS A 432
LEU A 115
 None
 1.33A 2zj0A-3o9pA:
undetectable		 2zj0A-3o9pA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 THR A 316
THR A 429
HIS A 432
LEU A 115
 None
 1.32A 3ce6A-3o9pA:
undetectable		 3ce6A-3o9pA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 THR A 316
THR A 429
HIS A 432
LEU A 115
 None
 1.31A 3ce6C-3o9pA:
undetectable		 3ce6C-3o9pA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		3 / 3 ASP A  42
SER A 507
ARG A  17
 None
 0.88A 3loqA-3o9pA:
2.2		 3loqA-3o9pA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 6 TYR A 272
PHE A 315
PRO A 479
LEU A 471
 None
 1.39A 3tgvB-3o9pA:
undetectable		 3tgvB-3o9pA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 TYR A 272
PHE A 315
PRO A 479
LEU A 471
 None
 1.45A 3tgvC-3o9pA:
undetectable		 3tgvC-3o9pA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		3 / 3 LYS A 355
PRO A 356
LEU A 357
 None
 0.80A 3tpxE-3o9pA:
undetectable		 3tpxE-3o9pA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 8 ARG A  41
GLU A  36
ILE A  40
ASN A 161
 None
 1.08A 4d33A-3o9pA:
undetectable		 4d33A-3o9pA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 7 ARG A  41
GLU A  36
ILE A  40
ASN A 161
 None
 1.07A 4d33B-3o9pA:
undetectable		 4d33B-3o9pA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 7 ARG A  41
GLU A  36
ILE A  40
ASN A 161
 None
 1.13A 4d39B-3o9pA:
undetectable		 4d39B-3o9pA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 8 PHE A 164
ARG A  99
ALA A  29
LEU A 100
PHE A 315
 None
 1.26A 4rkuA-3o9pA:
undetectable
4rkuJ-3o9pA:
undetectable		 4rkuA-3o9pA:
22.06
4rkuJ-3o9pA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 9 PHE A 164
ARG A  99
ALA A  29
LEU A 100
PHE A 315
 None
 1.28A 4y28A-3o9pA:
undetectable
4y28J-3o9pA:
undetectable		 4y28A-3o9pA:
21.72
4y28J-3o9pA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 12 PHE A 424
PHE A 109
GLY A 269
LEU A  34
PHE A 162
 None
None
None
MHI  A 516 (-3.7A)
None
 1.13A 5fsaA-3o9pA:
undetectable		 5fsaA-3o9pA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 6 ASP A 211
ARG A  77
ASN A  79
ASN A 187
 None
 1.18A 5l6eA-3o9pA:
undetectable		 5l6eA-3o9pA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 12 PHE A 424
PHE A 109
GLY A 269
LEU A  34
PHE A 162
 None
None
None
MHI  A 516 (-3.7A)
None
 1.13A 5v5zA-3o9pA:
undetectable		 5v5zA-3o9pA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 ARG A 297
MET A 300
THR A 301
LEU A 305
 None
 1.34A 5x19J-3o9pA:
undetectable		 5x19J-3o9pA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 ARG A 297
MET A 300
THR A 301
LEU A 305
 None
 1.39A 5x1bJ-3o9pA:
undetectable		 5x1bJ-3o9pA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 VAL A 386
PRO A 356
GLY A 352
TYR A 351
 None
 1.12A 5x80A-3o9pA:
undetectable
5x80B-3o9pA:
undetectable		 5x80A-3o9pA:
16.11
5x80B-3o9pA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		3 / 3 LEU A 427
THR A 277
ASN A 276
 None
 0.70A 6baaE-3o9pA:
undetectable		 6baaE-3o9pA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		3 / 3 LEU A 427
THR A 277
ASN A 276
 None
 0.70A 6baaF-3o9pA:
undetectable		 6baaF-3o9pA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		3 / 3 LEU A 427
THR A 277
ASN A 276
 None
 0.70A 6baaG-3o9pA:
undetectable		 6baaG-3o9pA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		3 / 3 LEU A 427
THR A 277
ASN A 276
 None
 0.71A 6baaH-3o9pA:
undetectable		 6baaH-3o9pA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 12 HIS A 314
THR A 270
ALA A 312
GLY A 416
THR A 423
 ZN  A 519 (-3.3A)
None
None
None
None
 1.24A 6hwdV-3o9pA:
undetectable
6hwdb-3o9pA:
undetectable		 6hwdV-3o9pA:
11.58
6hwdb-3o9pA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		5 / 12 HIS A 314
THR A 270
ALA A 312
GLY A 416
THR A 423
 ZN  A 519 (-3.3A)
None
None
None
None
 1.25A 6hwdH-3o9pA:
undetectable
6hwdN-3o9pA:
undetectable		 6hwdH-3o9pA:
11.58
6hwdN-3o9pA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 8 TYR A 506
VAL A 504
ASN A 500
ASN A  51
 None
 0.92A 6hzpA-3o9pA:
undetectable		 6hzpA-3o9pA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN
(Escherichia
coli) 		4 / 5 ARG A 297
MET A 300
THR A 301
LEU A 305
 None
 0.94A 6nknW-3o9pA:
undetectable		 6nknW-3o9pA:
9.06